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Delighted to present our new preprint on spatial multi-omic profiling of COVID-19 placentitis, a rare complication of maternal SARS-CoV-2 infection, resulting in poor fetal outcome tinyurl.com/2uypkdux (1/12) Lunaphore (a Bio-Techne brand) @nanostringtech Birmingham Tissue Analytics Matthew Pugh

Great to be at ⁦@nanostringtech⁩ offices in Amsterdam today, getting a VIP overview of enormous advances in spatial profiling from CSO, Joe Beecham ⁦@scienceirel⁩ ⁦All-Island Cancer Research Institute (AICRI)⁩ ⁦HEA⁩ ⁦UCD Conway Institute⁩ ⁦HealthResearchBoard⁩ ⁦University College Dublin⁩

[Tweeting a week late!] Check out my paper in Immunity on Th2 cells, macrophages and nematodes. Judi Allen tweeted the main take-home messages last week, but let me add some thoughts on where we can go from here, and get in a few words of gratitude. cell.com/immunity/fullt…

This study by Pearce, Brown, Middleton, Roberts, Moss et al. highlights PD-1 and TIGIT, as well as their ligands, as potential targets for combinatorial therapy for #pancreaticcancer. Read more here: bit.ly/3KEQlN7 Sarah Powell-Brett #immunology #CIRReviewerStar

#OpenAccess in Cancer Immunology Research Tissue-Resident Memory T Cells in #PancreaticCancer Coexpress PD-1 and TIGIT and Functional Inhibition Is Reversible by Dual Antibody Blockade aacrjournals.org/cancerimmunolr…

Meet Dr Eanna Fennell MSCA Global Fellow (2022)

Interested in novel targets? Take a look at this study highlighting PD-1 and TIGIT, as well as their ligands, as potential targets for combinatorial therapy for #PancreaticCancer— bit.ly/3MPOVAL Sarah Powell-Brett #CIRReviewerStar #Immunology #AACR23

Study of 18 355 infants found male but not female babies born to mothers with a SARS-CoV-2 +ve test during pregnancy, were more likely to have neurodevelopmental diagnosis in the first 12 months, even after accounting for preterm delivery. Éanna Fennell jamanetwork.com/journals/jaman…

Delighted to host EHS Research Marie Curie information session. Superb insights offered by 3 of our 2022 Marie Skłodowska-Curie Actions Fellows. Thanks Éanna Fennell Sven Messing Elaine Smith, PhD and @elainekinsella. Looking forward to supporting 2023 applicants. MarieS-Curie Ireland

This study by Pearce, Brown, Middleton, Roberts, Moss et al. highlights PD-1 and TIGIT, as well as their ligands, as potential targets for combinatorial therapy for #pancreaticcancer. Read more here: bit.ly/3V34pmY Sarah Powell-Brett #Immunology #CIRReviewerStar

1/ 🤰What can we learn about pregnancy form 45 million lab tests? We present a dynamic atlas of pregnancy and postpartum based on measurements from over half a million pregnancies at a one-week resolution. bioRxiv Alon Bar

How does the Epstein-Barr virus (EBV) drive immune changes/disease? 🦠 Hear Éanna Fennell discuss how he uses #spatialphenotyping on #PhenoCycler to elucidate the immune microenvironment of EBV-infected cells & shine new light on how #EBV drives #cancer. bit.ly/3O8BhJ1

Learn about technology & services at the LDCRC Single Cell Core and the National Tissue Spatial Profiling Platform at Limerick All-Island Cancer Research Institute (AICRI) Dr. Sudipto Das Research Ireland CRT in Artificial Intelligence Cathal Seoighe Genomics Data Science - SFI CRT @Bioinformatics Liam Gallagher 10x Genomics UL Research Follow @HSEMidWest John Greally

How is #spatialphenotyping uniquely suited to outline one of the putative causative relationships between #EpsteinBarrvirus infections, immunosuppression & cancer? Tune in on July 27th to hear Éanna Fennell answer questions like this and more. bit.ly/3O8BhJ1 #EBV

Tired of inaccurate cell classification? Need a way to quantify non-cellular features like ECM? You're in luck! Pipeline from Candace Liu for automated pixel classification in high-dimensional tissue images is out. Human BioMolecular Atlas Program (HuBMAP) nature.com/articles/s4146…

Alright, #GESTALT has grown beyond our expectations! To those subscribed: watch your inbox for open slots in our 𝑶𝒓𝒈𝒂𝒏𝒊𝒛𝒊𝒏𝒈 𝑪𝒐𝒎𝒎𝒊𝒕𝒕𝒆𝒆. If you're driven, eager to make an impact, and IMPORTANTLY have time to contribute, you could be the one we're looking for!

Biallelic loss of ATMcauses ataxia-telangiectasia, a congenital disorder associated with a high incidence of cancer, often diffuse large B-cell lymphoma (DLBCL). A new mouse model studies DLBCL in constitutional ATM loss. haematologica.org/article/view/h…

Molecular and spatial analysis of tertiary lymphoid structures in Sjogren’s syndrome nature.com/articles/s4146… Nature Communications Francesca Barone

Training has been going well so far but today marks day 1 of a 16 week training block.