Did we conceive the structure of neurons incorrectly all these years? nature.com/articles/s4159… Nature Neuroscience not smooth, cylindrical strands but a string of pearls? it's controversial science.org/content/articl… News from Science Science Magazine

This new study, led by Shigeki Watanabe & partially conducted in the MBL’s Neurobio course, challenges a fundamental tenet in neuroscience about the shape of axons & proposes a new model for understanding how information is transmitted in the brain. 🧪 🧠 mbl.edu/news/string-pe…

Study finds axons are not the cylindrical tubes pictured in books but more like pearls on a string. Article Link: oneneurojhu.org/2024/12/10/stu… “Understanding the structure of axons is important for understanding brain cell signaling,” says Shigeki Watanabe, Ph.D., associate professor

Announcing the first annual Visual Neuroscience summer course, Woods Hole, MA, Aug 1-16, 2025. Come for an eye-opening, hands-on experience with inspiring faculty and students from around the world. Please help spread the word!

Fresh preprint of some of my PhD work released today: if you like human synapses, STED and time-resolved EM check it out! "Ultrastructural membrane dynamics of mouse and human cortical synapses" biorxiv.org/content/10.110…

super excited to share that our new study is published Nature Neuroscience!! Here we show that intersectin and endophilin form condensates between the active zone and the reserve pool and maintain synaptic vesicles near the active zone for rapid replenishment. rdcu.be/evi5y

Endophilin-Intersectin collaborative work is now out at Nature Neuroscience nature.com/articles/s4159…. Endophilin has a direct role in synaptic vesicles exocytosis, in addition to its other functions. Thanks to watanabe lab 🔬 lab at Johns Hopkins & Milovanovic lab at DZNE labs

New preprint from Wei-Chung Allen Lee @darbly.bsky.social lab, Brian DePasquale lab, and my lab! If you love (or hate) mosquitoes, have a look: doi.org/10.1101/2025.0… We used TEM to describe the circuitry used for CO2 detection by mosquitoes. As usual with mosquitoes, nothing is as expected! 🌬️🦟