Critical analysis of the evidence for the SARS-CoV-2 origin hypotheses: a new OA editorial that summarizes the scientific evidence that informs the debate. Co-published in ASM journals, JVirology Editors, mSphere, and mBio. doi.org/10.1128/jvi.00…

Tweetorial! NINJ1 drives plasma membrane rupture, out today 📰. We are thrilled to share this collaborative effort detailing how cells rupture and die from cell-based assays down to the cryo-EM structure. See below for some brief highlights. nature.com/articles/s4158…

🚨PhD position opening in our lab at the Department of Immunobiology (DIB) in Lausanne! We are searching for a curious and motivated PhD student to study #innateimmunity, #inflammasomes or #NINJ1-induced cell death. For details: tinyurl.com/PBDIB Please RT and/or apply!

Have a look at the updated Bosse-lab.org/herpesfolds! We streamlined the table and annotated many more protein homologs, in part based on structure similarity. Isoforms are now also included. It’s the ultimate herpes cheat sheet! Let us now if we missed anything

Get your applications in— can’t wait to meet my new virology colleagues! Feel free to reach out if you have questions.

Hi science twitter I need some contamination help. Anyone seen this before? We see white dots visible by eye and it looks like piles of dead cells under the microscope. It can be transferred via contaminated media and has infected a range of our adherent cells…293t, hela, 3t3 🤔

NINJ1 induces plasma membrane rupture and release of damage-associated molecular pattern molecules during ferroptosis | The EMBO Journal embopress.org/doi/full/10.10…

We're looking for a #postdoc to join our team at the University of Lausanne (Switzerland) working on #inflammasomes, #celldeath and infectious diseases. Apply here and join us! tinyurl.com/3dyk6vhs

More than 100 EMBO Fellows are meeting in Heidelberg. The postdoctoral fellows present their research, attend a mentoring session, receive training on a variety of topics and more. #EMBOat60

The lab's latest NINJ1 story is out on bioRxiv 🥳 Ninjurin-1 mediated plasma membrane rupture is a two-step process requiring cell swelling biorxiv.org/content/10.110…

Here's our model of how NINJ1 oligomerization is a two step process where a first signal leads to NINJ1 oligomerization and cell swelling functionalizes the oligomers into lesions. biorxiv.org/content/10.110…

In a second preprint, postdoc Ella Hartenian and lab member Magalie show that NINJ1 is a restriction factor for HSV-1 in mouse macrophages biorxiv.org/content/10.110… We see that NINJ1 -/- cells are more infected than WT controls

The Lawrence Lab website (lawrence-lab.org) is live and we are hiring! We combine high resolution structure🔬 and cell biology🧫🧪 approaches to define mechanisms of stress response signaling in health and disease. Live postings at technician and postdoc levels: PLZ RT!

And it’s out! Here’s our story looking at a new role for ninj1 preventing hsv-1 endocytic entry into mouse macrophages. Nothing like viruses to teach you new things about proteins you thought you understood! EMBO Reports embopress.org/doi/full/10.10…

What a week! Here’s a review Elliott and I co wrote with Petr as a primer on ninj1 and how it works #celldeath Current Biology Elliott Bernard Broz Lab cell.com/current-biolog…