🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

**Funded PhD studentship at University of Bristol - to develop methods for applying Mendelian randomization in diverse populations and to apply these to identify risk factors for gallbladder cancer findaphd.com/phds/project/p…

A limited number of in-person places now available at the “Mendel @ 200” meeting 20-21st July. shop.bris.ac.uk/conferences-an…

From pea plants to better understanding of public health ... our upcoming conference celebrates the 200th birthday of Gregor Mendel, his legacy and the range of research his work has inspired. Join us in person in Bristol or online on 20-21 July #Mendel200 bristol.ac.uk/integrative-ep…

See the programme for our upcoming #Mendel200 conference to celebrate the bicentenary of Gregor Mendel. A great line up of speakers and topics. Join us online (free) or in person in Bristol, UK (small, subsidised price) bristol.ac.uk/integrative-ep…

Excited to thumb through an actual hard copy of the book “Combining Human Genetics and Causal Inference to Understand Human Disease and Development” edited with Rebecca Richmond and Jean-Baptiste Pingault, a thread on what it contains /cont

Our preprint “Separating the effects of early and later life adiposity on colorectal cancer risk: a Mendelian randomization study” is now available: medrxiv.org/content/10.110…

Finally: causal estimates for adiposity & metabolomic traits at scale! Pleased to share the first large-scale comparison of conventional vs MR approaches in UK Biobank in The Lancet Reg Health-Europe sciencedirect.com/science/articl… Key takeaways:

Interpretation of Mendelian randomization using a single measure of an exposure that varies over time dlvr.it/SV5x4N

Estimation of causal effects of a time-varying exposure at multiple time points through multivariable mendelian randomization dlvr.it/SV6bJ6

This is happening tomorrow! Thank you to all our speakers, helpers and all who've registered to join us (not too late if you want to join us online!). See you tomorrow! #Mendel200

New preprint out! In it we propose a (simple!) solution to the bias caused in Mendelian randomization from covariate adjusted GWAS statistics doi.org/10.1101/2022.0… Led by PhD student Joe Gilbody, also thanks to M Carolina Borges and george davey smith!

Mendelian randomization outlined by ⁦Eleanor Sanderson⁩ at #Mendel200

New paper assessing causality of DNA methylation associations with prevalent type 2 diabetes. Congratulations to Diana Juvinao for leading the work, very lucky to work with you! caroline relton Eleanor Sanderson @ammegandchips MRC IEU #diabetes #MR medrxiv.org/cgi/content/sh…

So excited to see our UK Biobank study comparing intergenerational instrumental variable analyses of BMI on mortality published in IJE !! academic.oup.com/ije/advance-ar… 🥳

Interpretation of Mendelian randomization using a single measure of an exposure that varies over time doi.org/10.1093/ije/dy…

This Primer explains Mendelian randomization - from concepts to required conditions - and describes key applications and applying the technique to growing genomic datasets Maria Glymour Michael V Holmes (he/him) Marcus Munafò Jean Morrison Chris Wallace 🇪🇺 🏳️‍🌈 go.nature.com/3x3IIJc

Check out our new Editor’s Pick from JBMRPlus Associate Editor Emma Clark Emma Clark! A Guide for Understanding and Designing Mendelian Randomization Studies in the Musculoskeletal Field @MRC_IEU BRistol Medical School (BRMS) Research University of Bristol (1/6) doi.org/10.1002/jbm4.1…

How much does a child's BMI affect their depression, anxiety, or ADHD symptoms? Not much, suggests our new research which accounts for family-level factors. Read it here: elifesciences.org/articles/74320. With Eleanor Sanderson @nm_davies @laurahowe_epi @alexhavdahl @bristimtom MRC IEU