Unraveling Alzheimer's complexities: T-N mismatch reveals specific non-AD factors in #Alzheimer's continuum. A comprehensive study linking T-N mismatch to comorbidities through in vivo and ex vivo measurements. alz-journals.onlinelibrary.wiley.com/doi/full/10.10… The National Institute on Aging (NIA) Alzheimer's Association Penn Medicine

Congratulations Dr. Linda Bagley and all the newest members of the Academy of Master Clinicians Penn Medicine

Excited to share our surface-based pipeline to parcellate 7T ex vivo postmortem human brain MRI at sub-millimeter native subject space resolution. We perform vertex-wise analysis in template space to link morphometry with histopathology! Paper: arxiv.org/abs/2403.19497 🧵(1/6)

Exciting times for #AI in healthcare. But certainly wasn’t as straightforward as everyone had expected! nature.com/articles/d4158…

New paper in Imaging Neuroscience by Pulkit Khandelwal, Paul A. Yushkevich, et al: Automated deep learning segmentation of high-resolution 7 Tesla postmortem MRI for quantitative analysis of structure-pathology correlations in neurodegenerative diseases doi.org/10.1162/imag_a…

The 2024 Glioma Post-Treatment BraTS has launched! Challenge website: synapse.org/#!Synapse:syn5… 1350 training cases available to download Arxiv: arxiv.org/abs/2405.18368 Maria CdeV Rachit Saluja MICCAI MICCAI Students

Happy Thursday! Check out this new publication that reveals patterns of medial temporal lobe vulnerability to tau pathology in Alzheimer’s disease in postmortem imaging. doi.org/10.1038/s41467… Eddie Lee, John Detre, David Irwin, David Wolk, Paul Yushkevich

Grateful to the Pendergrass Symposium and Penn Radiology for this opportunity to present our exciting work & receive Magna Cum Laude award.Kudos to my brilliant friend Behnaz Khazai for her tireless work on this project!And a heartfelt shoutout to my amazing mentor Mariam Aboian

Happy Tuesday, as you're going through your week check out this new publication that examines if there is a role for radiomics analysis in neuroimaging. doi.org/10.2463/mrms.r… David Wolk

Join Penn Neuroradiology this Sep for Neuroimaging in the Adirondacks: The Peaks and Valleys of CNS Imaging! Earn #CME with us in the magic of the Adirondack Mountain during peak foliage season. Use code “RADFRIEND10” & enjoy 10% discount on registration. cvent.me/knMa5o?RefId=R…

Surprise - FTLD-TDP Type C is a dual proteinopathy! Annexin A11 co-accumulates with TDP-43 in all cases of FTLD-TDP Type C. #annexinopathy #FTD #dementia #ADRD #ActaNeuropathologica doi.org/10.1007/s00401…

PET imaging shows different brain activity in people taking methadone or buprenorphine for opioid use disorder, according to a recent study.👇 buff.ly/4c8nqMD #radiology #NuclearMedicine #molecularimaging @SNMI_MI

Our colleague, #clinical #scientist, Jacob Dubroff, MD, PhD, presented evidence at the SNMMI annual meeting using PET imaging showing different brain activity in people taking methadone or buprenorphine for opioid use disorder. Learn more - spr.ly/6017gYg0c (1/6)

This cardinal just loves your home ChristiansonLaboratory

I am speaking at The Eastern Neuroradiological Society (ENRS) Annual Meeting 2024. Please checkout the details of my talk at: whova.com/xems/apis/open…

Please stop by poster # 169 today Saturday (07/27) Neuroimaging PIA #AAIC2024 #AAIC24 Alzheimer's Association to learn about our new parcellation scheme for 7T ex vivo human brain MRI to perform vertex-wise analysis to link morphometry with histopathology! PICSL Penn Memory Center

So excited that this is finally out! Was a superfun collaboration with Nicola Spotorno Very striking association of CSF asyn pathology with nucleus basalis of Meynert volumes, even in asymptomatic stages! Also some hints of associations with my favorite brain region, the MTL.

Penn researchers and clinicians are making waves at #AAIC24! Dr. Christopher Brown (far right, first photo) presented on tau pathology transmission, and Pulkit Khandelwal (far right, second photo) highlighted high-res 7T MRI for neurodegenerative diseases.

Great start to the International Society for Frontotemporal Dementias Workshop on Defining the #FTD and #ALS Spectrum — multi-disease perspectives spanning LATE-TDP, PLS, PMA, and VCP from David Wolk, Michael van Es, and Eddie Lee Eddie Lee Penn Memory Center