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CryoET 101 has officially launched! Check out the first chapter, made in collaboration with Julia Brasch (Julia Brasch) and Peter Shen. cryoem101.org/chapter-1-et/

Structural and functional analyses of a GPCR-inhibited ion channel TRPM3. Congrats! Chen. A very cool story from an extremely talented scientist and a wonderful friend. cell.com/neuron/fulltex…

Our manuscript on understudied GluN2C- and 2D-containing NMDAR is published online today. This project was one of many ‘homework’ given to us by #John_Lisman, who suggested GluN2C hypofunction be involved in schizophrenia. 1/4) authors.elsevier.com/a/1f%7Ew43vVUP…

Cryo-EM structure of a voltage-gated ion channel in polarized vesicles. Super cool work from my colleague Shiva in the MacKinnon lab! pnas.org/doi/10.1073/pn…

A structural biology community assessment of AlphaFold2 applications 構造生物学者、AlphaFoldを評価してみた。結果 うん、構造以外の分野でも広く使えそうやで nature.com/articles/s4159…

Architecture of chloroplast TOC-TIC translocon supercomplex biorxiv.org/cgi/content/sh…

Ion permeation pathway within the internal pore of P2X receptor channels biorxiv.org/content/10.110…

Structure of human phagocyte NADPH oxidase in the resting state dx.doi.org/10.7554/eLife.…

Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor dx.doi.org/10.7554/eLife.…

BPS Membrane Transport Subgroup is accepting nomination/self-nomination for Secretary-Treasure (3-year term, progressing to Chair for 2026 meeting). Deadline Dec 5: biophysics.org/forums?topics=…

Introducing newly minted Dr. Mihaljevic @Lyoobitsa for Qiu Lab! BCMB Graduate Program at JHMI She will join David Baker Lab Institute for Protein Design for postdoc to design ion channels from scratch. Best wishes for your future adventure!

Best Christmas Present = fully formatted pub. Congrats Bryan UTSA NDRB and thanks for the awesome collaboration Hojoon Lee Regional specialization of the tongue revealed by gustatory ganglion imaging cell.com/iscience/fullt…

Happy New Year! Excited to share our new work eLife - the journal on a unique desensitization mechanism of proton-activated chloride channel Last of a series of beautiful work on PAC by amazing James O-Owusu Kudos also to long-term collaborator Zheng Ruan DuLuLabs doi.org/10.7554/eLife.…

Do glia regulate drug addiction? Led by brilliant Junhua Yang, our new study Neuron shows VTA astrocytes modulate cocaine reward by tonically releasing GABA via SWELL1 large-pore #ionchannels Thx @NINDSnews @KlingensteinOrg McKnight Foundation for $$ authors.elsevier.com/a/1gSTD3BtfH1Z…

Congratulations @Lyoobitsa on this interesting & unexpected discovery of extracellular PIP2 binding of PAC #IonChannels, thanks Zheng Ruan DuLuLabs for solving the structure! Inhibition of the proton-activated chloride channel by PIP2 elifesciences.org/articles/83935

Our department of structural biology is hiring!

Pew biomedical programs are celebrating four decades of support for early-career researchers—Pew scholars and fellows who have gone on to reshape medicine, advancing cancer research, neuroscience, genomics, and more. pewtrsts.org/4iDVvX8

Excited to announce the Channels, Receptors, and Transporters (CRT) Subgroup Symposium at the 70th BPS annual meeting in San Francisco.