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Drug Discovery News

@drugdiscovnews

We provide engaging stories that help life science researchers keep current on the latest news in translational, preclinical, and clinical research.

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linkhttp://drugdiscoverynews.com calendar_today20-02-2020 14:25:14

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“People think of statistics as just sitting at the computer and working on math and methods, but we're really motivated to develop these statistics to improve public health,” Rebecca Kahn CDC told Stephanie DeMarco, PhD about her maternal GBS vaccine model. ow.ly/74tq50TfCg1

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The 2024 mpox outbreak involves a deadlier strain than the 2022 outbreak. Researchers developed an mRNA vaccine, mRNA-1769, which shows stronger protection than the traditional MVA vaccine and could improve responses to future outbreaks. ow.ly/2qsC50Thz27

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Dopamine is in organs besides the brain, which might explain the systemic side effects of antipsychotics. Modified bromocriptine selectively stimulated pancreatic dopamine receptors and may compete with antipsychotics, reducing metabolic side effects. ow.ly/9nsz50TgzPQ

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Researchers are trying out some pretty unexpected ways to get the heart to regenerate after a heart attack. Jens Tank DLR - English told Allison Whitten, PhD about his team’s work putting patients into the largest hypoxic chamber in the world. 🎧 Listen here: ow.ly/OVf650SXPqU

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In 2010, scientists described plectasin’s mechanism using micelles, but these didn’t mimic real membranes. Researchers Utrecht University found that in biological membranes, plectasin forms large supramolecular structures to disrupt bacterial cell walls. ow.ly/NwUT50T8OUx

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The future of toxicology is bright with the integration of advanced technologies like spatial transcriptomics and AI. Learn how these innovations are shaping drug development and improving patient outcomes. Read the interview here: ow.ly/hBNF50T9VP7

The future of toxicology is bright with the integration of advanced technologies like spatial transcriptomics and AI. 

Learn how these innovations are shaping drug development and improving patient outcomes.

Read the interview here: ow.ly/hBNF50T9VP7
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A decade of research pointed scientists to LRIG1 as a key player in T cell inhibition, potentially explaining why some patients resist immunotherapies. ow.ly/pGKp50T9Kc3

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Tumors constantly release fragmented DNA into the bloodstream. Join us for a webinar with Shervin Tabrizi, MD Broad Institute to hear his breakthrough method for capturing tiny circulating tumor DNA pieces and improving early cancer detection. Register now: ow.ly/gV7250ThRAi

Tumors constantly release fragmented DNA into the bloodstream.

Join us for a webinar with <a href="/ShervinTabrizi/">Shervin Tabrizi, MD</a> <a href="/broadinstitute/">Broad Institute</a> to hear his breakthrough method for capturing tiny circulating tumor DNA pieces and improving early cancer detection.

Register now: ow.ly/gV7250ThRAi
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Using the antibody mAb77, Erica OllmannSaphire and her team La Jolla Institute mark a significant milestone in fighting measles. This antibody could be the key to developing new antiviral therapies. Read more: ow.ly/qjTl50T6ZJT

Using the antibody mAb77, <a href="/EOSaphire/">Erica OllmannSaphire</a> and her team <a href="/ljiresearch/">La Jolla Institute</a> mark a significant milestone in fighting measles. 

This antibody could be the key to developing new antiviral therapies.

Read more: ow.ly/qjTl50T6ZJT
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Paralysis due to spinal cord injury is a permanent, life-altering condition – but it doesn’t have to be. Researchers @HKUMed engineered stem cells that help mice regain control of their muscles. Read about it in this new story by Samantha Borje. ow.ly/QS6P50TeL9N

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ICYMI, our September 2024 issue is out now! Explore how: 🟢 Green light therapy could alleviate chronic pain 🟢 The vagus nerve links digestion, mood, and health 🟢 A topical drug can stop skin cancer at the source 🟢 And much more! Read it all here: ow.ly/y0RU50Tnkqt

ICYMI, our September 2024 issue is out now!

Explore how:
🟢 Green light therapy could alleviate chronic pain
🟢 The vagus nerve links digestion, mood, and health
🟢 A topical drug can stop skin cancer at the source
🟢 And much more!

Read it all here: ow.ly/y0RU50Tnkqt
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This week is World Mitochondrial Disease Week. Follow along as we share relevant stories about the current research! You can also dive into our latest stories about mitochondria, here: ow.ly/ulm350Tnh3Y #WorldMitoDiseaseWeek

This week is World Mitochondrial Disease Week.

Follow along as we share relevant stories about the current research!

You can also dive into our latest stories about mitochondria, here: ow.ly/ulm350Tnh3Y

#WorldMitoDiseaseWeek
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Researchers Wake Forest University School of Medicine have given the powerhouse of the cell, mitochondria a new job: revitalizing damaged kidneys. Read about it in this new story: ow.ly/5aQ450Tnhc3

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Scientists at the DKFZ led by Michael Platten 🇪🇺 showed that natural killer cells can eliminate activated T cells via the immune checkpoint ligand B7H6. This has implications for treating cancer with T cell-based immunotherapies. ow.ly/1rny50Tnb5Y

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Drugs can have a great influence on fertility, reproduction, and development. In this webinar brought to you by Inotiv, learn how to use pathology data to evaluate drug effects on development and reproduction in juvenile animal studies. Register now: ow.ly/yCiA50ThSNH

Drugs can have a great influence on fertility, reproduction, and development.

In this webinar brought to you by <a href="/inotivco/">Inotiv</a>, learn how to use pathology data to evaluate drug effects on development and reproduction in juvenile animal studies.

Register now: ow.ly/yCiA50ThSNH
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The dose makes the poison. A small amount of a toxic gas could forestall symptoms of aging. Researchers University of Exeter treated worms’ mitochondria with hydrogen sulfide to enhance their lifespans and health. ow.ly/JQSO50TnhFF

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Dopamine dysfunction during adolescence can lead to development of various neuropsychiatric disorders. Gabriela Carolina Lopez (Gaby) reports on a recent study from University of Rochester that showed how dopamine neurostimulation can rescue adolescent cognitive deficits. ow.ly/7kS350Tnbvw

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3D bioprinted tumors can improve cancer research by better replicating tumor microenvironments, enabling precise drug screening, and potentially guiding personalized therapies. Read more from Alejandra Manjarrez: ow.ly/AAK650SXQGx

3D bioprinted tumors can improve cancer research by better replicating tumor microenvironments, enabling precise drug screening, and potentially guiding personalized therapies. 

Read more from <a href="/lecteroide/">Alejandra Manjarrez</a>: ow.ly/AAK650SXQGx