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BIG NEWS in Cell Reports! Adhesion strength of tumor cells predicts metastatic disease in vivo cell.com/cell-reports/f… In this work, we show that a physical property - adhesion strength - stratifies mouse and patient samples into disease and non-disease subtypes. (1/4)

PIEZO1-dependent mode switch of neuronal migration in heterogeneous microenvironments in the developing brain dlvr.it/TJR5gG

A new chapter has begun for two of the world’s most popular preprint platforms, bioRxiv and medRxiv, with the launch of a non-profit organization that will manage them go.nature.com/41IRQkm

Distinct cellular mechanisms underlie chemotherapies and PD-L1 blockade combinations in triple-negative breast cancer dlvr.it/TJSQXf

Metabolic engineering to facilitate anti-tumor immunity dlvr.it/TJTtYM

Thrilled to share our new study on CAFs and NK cells, now online 🌟 in CD!! NK cells are ideal candidates for cancer killing since they don't need antigen specificity. But they are usually not active in tumors. We wondered whether this could be due to inhibition by CAFs 🧵👇

🚨 Paper Alert 🚨 Absolutely delighted to share our last paper on "spatial mechano-transcriptomics" in Nature Methods👇!! nature.com/articles/s4159…

📢 NIH BioArt Source, a free science and biomedical art resource library, offers an array of high-quality illustrations, vectors, & brushes, free to use & download. See the full catalog of free science and #biomedical illustrations: bioart.niaid.nih.gov #FreeResource

When you don't have new results to show in your lab meeting

Fascinating in vivo tracking of collective cell migration under confinement PNASNews! Reveals self-organized antiparallel streams and compressive ECM deformation. Now wondering: How do single cells navigate these complex microenvironments? 🤔 -LY www-pnas-org.libproxy1.nus.edu.sg/doi/10.1073/pn…

Online Now: Conserved spatial subtypes and cellular neighborhoods of cancer-associated fibroblasts revealed by single-cell spatial multi-omics dlvr.it/TJnywK

A bit late to the party, but finished Lessons in Chemistry by Bonnie Garmus. POV as a reader: captivating, funny, gripping story, relatable in professional sense. As a woman in science: Fantastic to see how far we’ve come, but some aspects still unfortunately resonate. Recommend!

Online Now: Pan-cancer human brain metastases atlas at single-cell resolution dlvr.it/TK6FLl

Excited to announce that MBI-MPG Conference 2025: Mechanobiology in Time and Space. Dates: 9-12 Sep 2025 Venue: Shaw Foundation Alumni House, NUS, Singapore Website: mbi.nus.edu.sg/events/mbiconf… The deadline for early bird registration is May 31, 2025 Join us!

Our latest paper on #cardiac #fibrosis is out today in nature. Congrats to Stanford CVI Stanford Medicine researchers led by @Sangkyun_Cho and Siyeon Rhee. And special thanks to computational scientists Greenstone Biosciences for providing #AI #drugdiscovery. Link: nature.com/articles/s4158…

Choking under pressure? 🥵 3D confinement in hydrogel-based culture inhibits muscle stem cell activation and differentiation. “…this #preprint demonstrates the interconnectedness of different subfields of biology.” #preLight of Justin ⬇️👀 prelights.biologists.com/highlights/3d-…

Come work with us! Seeking a Research Associate/Fellow to work on our NHMRC funded project using nanofabrication to model tumour ECM structures. Centre for Cancer Biology

How do altered levels of lamins and other nuclear envelope proteins contribute to cancer metastasis, and how does this relate to #mechanobiology? Learn more in our recent review by Sarah Henretta now out in npj Journals - biological physics and mechanics (doi.org/10.1038/s44341…).

🧫 Researchers demonstrated that ECM stiffness is significantly higher in endometrial cancer tissues compared to normal endometrium, correlating with elevated expression of ROCK1, a mechanosensitive kinase. CDD press | go.nature.com/3YL7Hyt

Thank you Mara Sherman Lab for this insightful spotlight on our recent paper in Cancer Discovery ! Love the title too 😍 - CAFs Defang NK Cells to Promote Breast Cancer Immunosuppression …crjournals-org.ezproxy.weizmann.ac.il/cancerdiscover…