Hi. I am Diane Jelinek; I am chair of the Department of Immunology at Mayo Clinic. My lab studies human B cell leukemia, myeloma. #cimchat

Yes, immunotherapy is based on how the immune system recognizes and eliminates pathogenic organisms. There are differences too. #cimchat

A2 It depends on how different the tumor cell is from normal cells. This dictates how well the imm system sees tumors. #cimchat

A2 whole genome sequencing of tumor is helping identify mutant proteins in tumor cells #cimchat

Without ongoing basic investigation into the immune system we wouldn't be where we are today. #cimchat

Depends on if the tumor cells express molecules that inhibit the immune system from attacking. #cimchat

A4 Possibly, but some chemotherapies will inhibit the immune response. #cimchat

Some antibody secreting plasma cells can survive for many years. #cimchat

As tumor cells continue to grow in patients there is a chance for more mutations to occur. #cimchat

A8. Often the treatment is targeted to something very specific, however, you can see same targets expressed in different cancers #cimchat

A8. Yes or other clinical trials that may be of value for their cancer. #cimchat

Signing off now! Thanks for hosting this chat....very informative and good to hear others' ideas! #cimchat