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Big congrats to Xinyu Ling, postdoc in the Sidi Chen lab Yale School of Medicine on becoming a Jane Coffin Childs Merck Fellow @JCChildsFund! Ling will investigate ways to improve cellular immunotherapies targeting solid tumors. 👏 👏🏿👏🏽👏🏾👏🏻

Three of the more costly and frequently used reagents in molecular biology are rolling circle amplification (RCA) mix, chemically competent MachOne (or other E. coli) cells, and Gibson assembly mix. Postdoc Julian Willis—who is starting his own lab in the UK soon—developed

Our lab finished the wonderful year in the past week by welcoming Dr. Xinyu Ling Xinyu Ling formal onboarding, a fun lab meeting with interesting science and games&gifts, and a lab dinner of celebration and appreciation! Very much look forward to the exciting new year! #XiaLab

Very exciting to start a new journey in Xia Lab！

MIT University released free online courses. No textbooks or fees required. Here are 10 courses you don't want to miss:

This week we held our Third Annual GRO Retreat Broad Institute and it was a blast! Thank you to our keynote speaker Benjamin Ebert, our visiting speaker Sara Mostafavi & all of our contributing discussion leaders, breakout participants, poster presenters. An incredible group!

I am thrilled to announce that the last part of my PhD thesis work got published in Nature Chemical Biology! We established RRENAPT system to track endogenous proteins based on RNA editing-mediated genetic code expansion. See the thread below: nature.com/articles/s4158…

A true curiosity-driven journey, fulfilling one of my childhood dreams! The tail loss marks a pivotal evolutionary step towards humans and apes. But how did it happen? rdcu.be/dzTba Itai Yanai Jef Boeke

The efficiency of prime editing is improved by exploiting a newly discovered small RNA-binding protein that mediates prime editing. nature.com/articles/s4158… #NBThighlight

How to pick a problem. Today in Cell. 1/53 cell.com/cell/fulltext/…

Excited to share a new preprint (biorxiv.org/content/10.110…) describing Precision Editing of Regulatory Sequences to Induce Stable Transcription-On (PERSIST-On), a hit-and-run strategy that enables robust and stable heritable gene activation in human cells. 1/15

GoT-ChA! I am thrilled to announce that our paper "Mapping Genotypes to Chromatin Accessibility Profiles in Single Cells" is now out in nature !! 👩‍🔬👨‍🔬🧬If you want to link somatic mutations to epigenetic changes directly in patient samples: nature.com/articles/s4158… 👇🧵

Meet Bo Xia, a systems biologist using both AI tools and experimental technologies to understand how the genome controls cell fate in health and disease. Learn about Bo in a #WhyIScience Q&A: broad.io/WISBo