Very happy to announce that Luca Delfinis Luca Delfinis, PhD in our lab will present his work next to leaders in cancer cachexia in Stockholm. Luca found 1) cancer causes weakness and mitochondrial stress before atrophy, 2) some muscles restore specific force! society-scwd.org/annual-confere…

Presenting our recently published work on behalf of Christopher Perry PhD in the 16th annual SCWD conference at the Karolinska Institute. What an amazing experience surrounded by an exceptional group of researchers! SCWD Journal of Cachexia, Sarcopenia and Muscle

Cancer cachexia is a muscle wasting syndrome that is associated with certain cancers. Research characterizing the multifactorial origins of this syndrome is still ongoing. Check out 3 recent publications that have made notable advances in this pub review: bit.ly/4925ces

The Cancer Cachexia Society Society Education Committee invites you to the fourth of our Trainee Talks on November 8th at 12:00 pm EST! Selected speakers: Deena Snoke, Luca Delfinis and Andrea Irazoki. Seminars are open to everyone, please share! See cancercachexiasociety.org for link!

For cancer patients, maintaining muscle is vital to health and treatment, but staying strong is complicated theconversation.com/for-cancer-pat… via The Conversation Canada

Women with advanced ovarian cancer experience severe muscle wasting once metastasis occurs Here, we describe a new mouse model of metastatic ovarian cancer cachexia that can be used to study this relationship We also found that weakness actually precedes metastasis and atrophy

Women with metastatic ovarian cancer experience severe muscle wasting Here, Luca Delfinis, PhD in our lab describes a new mouse model to help study this relationship We also found that weakness actually precedes metastasis and atrophy Molecular Metabolism is fast! 1/ sciencedirect.com/science/articl…

Muscle Health we need to all congratulate Luca on his exceptional #PhD defence under the outstanding mentorship of prof Christopher Perry PhD #cancer #muscle York University

Very proud to announce the newly minted Dr. Luca Delfinis! Luca Delfinis, PhD will have a fantastic career and be respected by his peers, as he is/was here in YorkUHealth. He will be missed but watch out for his next big steps in industry.

Here are Luca's published first author papers. His last paper is about to be submitted! Muscle weakness precedes atrophy during... Ovarian cancer cachexia: pubmed.ncbi.nlm.nih.gov/38925248/ C26 colorectal cancer: pubmed.ncbi.nlm.nih.gov/36346680/

We are proud to introduce Dr. Luca Delfinis, who has successfully defended his PhD! As a doctoral student in Christopher Perry PhD's lab, Luca studied the links between metabolic dysfunction & cancer cachexia to advance a treatment for this illness. Many congratulations, Luca! 👏#YorkU

Congrats to Shahrzad Khajehzadehshoushtar Shahrzad Shoushtar for an outstanding MSc defence! Shar is nominated for a thesis prize for a carefully crafted document, voluminous work, + high-level discussion Watch for Shar's publication on mitochondrial therapy in ovarian cancer cachexia

Seeing these two convocate at the same time was a special experience for me. Shahrzad Khajehzadehshoushtar Shahrzad, MSc, and Luca Delfinis Luca Delfinis, PhD, PhD. This duo poured their passion into a huge shared project on ovarian cancer-induced cachexia. Onward and upwards!

Our 3rd new manuscript this week: Luca Delfinis, PhD found a mitochondrial-targeted compound partially prevents muscle weakness without preventing atrophy in ovarian cancer. This opens a new direction for therapies targeting muscle ‘quality’. biorxiv.org/content/10.110…

Published research from recent #YorkU Kinesiology & Health Science YorkU KINE PhD grad Luca Delfinis is the first to show muscle weakness precedes muscle wasting in cancer – a groundbreaking discovery for early detection & treatment. tinyurl.com/533x3prn

When is a change in mitochondrial bioenergetics reflective of 'mitochondrial dysfunction' vs 'intentional reprogramming'? Here we present traditional vs alternative interpretations of mitochondrial responses to muscle disuse. physoc.onlinelibrary.wiley.com/doi/10.1113/JP…

The term mitochondrial dysfunction is often misnomer Something that looks “dysfunctional” with a single approach can end up being an adaptive recalibration when seen more holistically with multiple measures Excellent paper below by Christopher Perry PhD