In my case - call me if you're interested in joining us to work on plasmid epidemiology!

Do not miss this!!!

The final version of our manuscript is out in Nature Communications!🤩 Mutations in the efflux pump regulator MexZ shift tissue colonization by Pseudomonas aeruginosa to a state of antibiotic tolerance Sara Hernando-Amado Signe Lolle Rigshospitalet DTU Biosustain 🧵👇nature.com/articles/s4146…

El año pasado me propusieron cumplir un sueño: ilustrar un libro. Pero encima, no un libro cualquiera. Un libro cuyo mensaje central es algo en lo que creo fuertemente: que la ciencia no es trabajo de individuos, sino un trabajo que solo tiene sentido en su colectividad.

First step in a community project to provide a uniformly assembled, annotated and searchable set of bacterial genomes, our preprint on our initial release of 1.9 million genome assemblies+taxonomic estimates. (figure compares with previous 661k dataset)
biorxiv.org/content/10.110…

Read the Review by Alvaro Sanchez Lab Alvaro San Millan discussing the relevance of epistasis patterns for predicting antimicrobial resistance evolution & generating hypotheses about the mechanisms ➡️embopress.org/doi/full/10.10… #antibioticresistance

📢Our next webinar, co-organized with ESGEM.SG, will feature Sonia Aracil-Gisbert 🇪🇸 on 'ICU environment contributes to the endemicity of the 'Serratia marcescens complex' in the hospital setting'📢

Chaired by Teresa M Coque & Angela Novais

📌escmid-org.zoom.us/webinar/regist…

ESCMID

Excited to share the first preprint from my lab, collaborating with the fantastic @alvsanmillan's lab, led by the amazing Jorge Sastre Domínguez . We've demonstrated how insertion sequences encoded in plasmids promote bacterial adaptation. This project has been incredibly fun!

New preprint in collaboration with Alfonso Santos-López lab and led by Jorge Sastre Domínguez. Combining experimental evolution and analyses of longitudinal samples from hospitalised patients, we unveiled a new mechanism of plasmid-mediated evolution beyond HGT 1/8
biorxiv.org/content/10.110…

New preprint alert! 🚀

Ever wondered about the relationship status between defense systems and HGT? 🧬 Well... it's complicated! Dive into our study where we dissect this intricate bond across thousands of microbial genomes! #Genomics #Microbiology

biorxiv.org/content/10.110…

Excited to share a new study from the lab, led by Rohan Maddamsetti, in Nature Communications. It reveals how antibiotic selection and mobile genetic elements (MGEs) could accelerate duplication of antibiotic resistance genes (ARGs) in the lab or in the wild. nature.com/articles/s4146… 1/n

In our first paper with our friends from Alvaro San Millan 's lab, we discuss whether the fitness effects of plasmids involved in AMR may be explained by the fitness of their host. We are working together on other exciting projects at the moment, so cheers to the first of many!

👇👇👇👇👇👇

Very happy to join this work just published in Microbiology Spectrum at the ASM with these super Portuguese and Danish teams. Special thanks to Ana R Freitas Louise Roer for the incredible work! 👇
Microbiología Clínica RyC 🧫🔬🦠 CIBERINFEC @GEMARA_SEIMC

Our new preprint is available :)
'Community context influences the conjugation efficiency of E. coli' Marjon de Vos
biorxiv.org/content/10.110…

We are offering a 3-year contract to a PhD student to join our laboratory as part of the Acinetowork project to design and develop a glycoconjugate vaccine as a treatment against MDR A. baumannii. Deadline on February 8th. Check the conditions here 👇🏽👇🏽 euraxess.ec.europa.eu/jobs/180974

How do phages/MGEs overcome bacterial defenses? Delve into our Nature Reviews Genetics review on 𝗶𝗻𝗵𝗶𝗯𝗶𝘁𝗼𝗿𝘀 𝗼𝗳 𝗯𝗮𝗰𝘁𝗲𝗿𝗶𝗮𝗹 𝗶𝗺𝗺𝘂𝗻𝗶𝘁𝘆!🛡️

We discuss discovery methods, classify mechanisms, & examine their biotech potential!🧬
nature.com/articles/s4157… 1/11

New preprint alert! 🚨

Our latest work on plasmid mobility with Eduardo Rocha & Amandine Nucci is now available.

Identification of novel origins of transfer across bacterial plasmids.

Read the full paper here:
biorxiv.org/content/10.110…

Thread🧵below!

UKHSA is hiring a bioinformatician in bacterial and fungal AMR. Permanent position £42-48K apply by 7 Feb. jobs.ac.uk/job/DFJ552/sen…

If any non-UK folk with (or soon to have) a PhD are interested in applying for a Newton International Fellowship to work with me at the University of Bath (UK) on pangenome algorithms for bacteria and/or plasmids, do get in touch!
Deadline 13th March!

royalsociety.org/grants-schemes…