DeLisa Research Group
@delisagroup
We are the DLRG. We engineer bacteria to solve problems in biology and medicine. @Cornell University.
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https://www.delisaresearchgroup.com/ 25-12-2013 16:37:03
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Congratulations to Belen Sotomayor for winning Merckโs Best Oral Presentation Award ๐ฅ and to Deepali for wining Corningโs Best Poster Presentation Award๐ฅ at the CBE Graduate Symposium! Delisa Lab is on fire, keep shining, team! #science
Congratulations to Belen Sotomayor on her induction into the ๐๐จ๐ฎ๐๐ก๐๐ญ ๐๐ซ๐๐๐ฎ๐๐ญ๐ ๐๐จ๐ง๐จ๐ซ ๐๐จ๐๐ข๐๐ญ๐ฒ at Yale University as one of the Cornell University representatives! Her leadership, scholarship, character, service, and advocacy embody this prestigious honor #STEM #Leadership
Congratulations to the Chatterjee Lab and Tina Ye from our lab on this exciting new publication! We introduce โdeubiquibodiesโ (duAbs) that selectively stabilize proteins. Our study is now available at Nature Communications ! #SyntheticBiology #ProteinEngineering
How are we going to develop more domestic manufacturing capability that can deliver medicines? #cellfree biotechnology can help. Check out our new manuscript on scalable cell-free protein synthesis w? Ashty Karim DeLisa Research Group Rochelle Aw doi.org/10.1002/bit.28โฆ
Congratulations to Belen Sotomayor on receiving the Spring ๐๐๐๐ ๐๐ฎ๐ฌ๐ญ๐ข๐ง ๐๐จ๐จ๐๐ฒ ๐๐ซ๐๐๐ฎ๐๐ญ๐ ๐๐๐ฌ๐๐๐ซ๐๐ก ๐๐ฑ๐๐๐ฅ๐ฅ๐๐ง๐๐ ๐๐ฐ๐๐ซ๐, the highest honor awarded to a graduate student by Cornell Universityโs CBE Department!
Antibodies are important therapeutics, but producing them in bacteria has been difficult due to glycosylation. w/ Matthew DeLisa Belen Sotomayor we discovered an enzyme that can glycosylate the native Fc acceptor sequence. Pretty cool. Nature Communications nature.com/articles/s4146โฆ
The test phase of biological design is too slow. How can we accelerate it? We show how cell-free systems can be used to speed up the study of post-translational modifications for RiPPs and glycosylation. Nature Communications nature.com/articles/s4146โฆ
More than 30% of the world's population lacks access to essential medicines. What if we could make medicines when and where they are needed? Enter #cellfree biomanufacturing. With DeLisa Research Group Matthew DeLisa we show a new approach to portable medicine making. biorxiv.org/content/10.110โฆ
PepMLM is out in Nature Biotechnology! ๐ญWant a short binder for any target? Just input its sequence + desired binder length โ PepMLM unmasks it. Simple? No way? The results speak for themselves. ๐ ๐: nature.com/articles/s4158โฆ ๐ป: github.com/programmablebiโฆ ๐ค: huggingface.co/ChatterjeeLab/โฆ
A wonderful article on PepMLM by Fay Lin, PhD in Genetic Engineering & Biotechnology News! ๐ Really captures how we think about sequence vs. structure and how, via experimental collaboration, we've gotten biologists (like Ray Truant, DeLisa Research Group, and Hector Aguilar-Carreรฑo) to believe in sequence-based design. ๐