#ARVO2022 don't miss the latest #NEIfunded iPSC-RPE studies looking at CFH risk variants and disease propensity.

News: Retinal cell map could advance precise therapies for blinding diseases dlvr.it/SPtycl

#NEIfunded researchers Kapil Bharti and Davide Ortolan developed a map of RPE cells -- identifying subpopulations with relevance to disease vulnerability. A big advance for gene and stem therapies for degenerative diseases. #regenerativemedicine bit.ly/3siV1ys

Creating a map of RPE cells subpopulations with differential retinal diseases sensitivity. Findings will help in developing precise cell & #GeneTherapies. Innovative work by @davideortolan91 @sharmaruchi29 @kapilbharti123 pnas.org/doi/10.1073/pn…

New work reveals that the retinal pigment epithelium (RPE) is made up of 5 distinct cell populations, each in a specific location. This explains location-dependent susceptibility to eye diseases. Kapil Bharti @sharmaruchi29 Davide Ortolan ow.ly/iYBV50J3mZr

Davide Ortolan, @SharmaRuchi29, Kapil Bharti and co map out #retinal pigment epithelium using #ArtificialIntelligence, which could lead to more precise therapies for degenerative eye diseases. bit.ly/3l4AzND

Mapping #retina pigment epithelial cells – greater understanding of cell types affected in #eye diseases. Video and research by Davide Ortolan et al Kapil Bharti NIH in PNASNews. Read more on bpod.mrc.ac.uk/archive/2022/6… with MRC Laboratory of Medical Sciences (LMS) and @EnricoStennito

Congratulations to NEI Intramural researcher Mitra Farnoodian Tedrick (from Gurmeet kumar) for receiving the Knights Templar Eye Foundation grant to help develop potential therapies for #Stargardt disease! bit.ly/3NKQXyM

News: First U.S. patient receives autologous stem cell therapy to treat dry AMD dlvr.it/SXYd0j

NIH I cannot thank the team enough. Over 10 years of efforts went into preparation for this day. I am honored to work such a dedicated team who made this happen. NEI NIH Common Fund Fujifilm Cellular Dynamics ARVO ISSCR ISCT @sharmaruchi29 Davide Ortolan

(1/2) Clinical trial surgery at NEI led by Kapil Bharti: #RPE patch developed from autologous #StemCells successfully implanted! 15 years' work: innovation in retinal biology, iPSCs, cell manufacturing, materials science, retinal surgery bit.ly/3AIVduq

Check out this #differentiation #protocol to generate pure #retinal pigment epithelium cells from induced pluripotent #stemcells, from Dr. Kapil Bharti's lab Kapil Bharti @sharmaruchi29 Davide Ortolan NEI: star-protocols.cell.com/protocols/1860

Online in STAR Protocols: #Differentiation #protocol to generate pure #retinal pigment epithelium cells from induced pluripotent #stemcells, from Dr. Kapil Bharti's lab Kapil Bharti @sharmaruchi29 Davide Ortolan NEI: hubs.li/Q01nFzdg0

Davide Ortolan provides a protocol he developed to perform single cell analysis of human RPE/choroid. His previous work in PNAS used this protocol and made a groundbreaking discovery of five RPE sub populations.

I'm excited to announce Kapil Bharti's selection as Scientific Director for the NEI. Kapil is a superb basic/translational scientist - he'll lead >20 labs, 6 core facilities, & 300 staff in our Intramural Research Program. bit.ly/3LaGO0o @KapilkBharti123

Thank you @sharmaruchi29 and Kapil Bharti for your mentorship throughout the years!! This would not have been possible without you! I'm very excited to start this new adventure 😁 Many thanks to NEI and BrightFocus Foundation for supporting my career!