Direct Comparison of Alternative Blood-Based Approaches for Early Detection and Diagnosis of HPV-Associated Head and Neck Cancers aacrjournals.org/clincancerres/…

🧬 Un nuevo enfoque probabilístico inspirado en simulaciones celulares para segmentar con precisión células en transcriptómica espacial. ➡️ Mejora la detección de células inmunes infiltradas como neutrófilos y linfocitos T. 🔗 nature.com/articles/s4159… #SpatialTranscriptomics

🇺🇸 NGS tumoral en cáncer de próstata metastásico revela diferencias raciales en alteraciones genómicas. 🔍 SPOP e inestabilidad microsatélites más frecuentes en hombres negros 🧪 TP53, mal pronóstico en todos los grupos jamanetwork.com/journals/jaman… #ProstateCancer #PrecisionOncology

🩸 Nuevo estudio modela el impacto de la frecuencia de test MCED (detección temprana de múltiples cánceres) en diagnóstico y mortalidad. 📆 Cribado anual: +370 cánceres detectados/año/100k, -49% en estadio avanzado, -21% muertes. bmjopen.bmj.com/content/15/5/e…

Comprehensive genetic profiling of sensorineural hearing loss using an integrative diagnostic approach cell.com/cell-reports-m…

The mutagenic forces shaping the genomes of lung cancer in never smokers nature.com/articles/s4158…

Ongoing genome doubling shapes evolvability and immunity in ovarian cancer nature.com/articles/s4158…

Complex genetic variation in nearly complete human genomes nature.com/articles/s4158…

Spatiotemporal T-cell tracking for personalized T-cell receptor T-cell therapy designs in childhood cancer. annalsofoncology.org/article/S0923-…

Human interpretable grammar encodes multicellular systems biology models to democratize virtual cell laboratories. cell.com/cell/fulltext/…

GWAS shows the genetics behind cell-free DNA and highlights the importance of p.Arg206Cys in DNASE1L3 for non-invasive testing sciencedirect.com/science/articl…

MammaPrint predicts chemotherapy benefit in HR+HER2- early breast cancer: FLEX Registry Real-World Data academic.oup.com/jncics/advance…

A methylome-wide association study of major depression with out-of-sample case–control classification and trans-ancestry comparison nature.com/articles/s4422…

DNA methylation cooperates with genomic alterations during non-small cell lung cancer evolution nature.com/articles/s4158…

Descanse en paz, Google Académico Voy a compartir los 10 prompts de Perplexity que convierten la investigación de una tarea ardua en un superpoder Cópialas y pégalas en Perplexity ahora mismo:

Population-scale Long-read Sequencing in the All of Us Research Program medrxiv.org/content/10.110…

Pathogenic Germline Variants in Cancer Susceptibility Genes jamanetwork.com/journals/jama/…

Improved specificity and efficiency of in vivo adenine base editing therapies with hybrid guide RNAs nature.com/articles/s4155…

The functional landscape of coding variation in the familial hypercholesterolemia gene LDLR science.org/doi/10.1126/sc…

Whole genome sequencing-powered ctDNA sequencing for breast cancer detection annalsofoncology.org/article/S0923-…