David Fajgenbaum, MD (@davidfajgenbaum) 's Twitter Profile
David Fajgenbaum, MD

@davidfajgenbaum

@Penn physician-scientist-patient who 'cured thyself' | Advancing @CureCastleman + @EveryCure | National Bestseller #ChasingMyCure ChasingMyCure.com

ID: 340440727

linkhttp://amazon.com/Chasing-My-Cure-Doctors-Action/dp/1524799637 calendar_today22-07-2011 18:11:10

3,3K Tweet

12,12K Followers

3,3K Following

Erik Brynjolfsson (@erikbryn) 's Twitter Profile Photo

Athletes from four California universities won 89 Olympic medals. (The United States won 126 total). Athletes from Stanford University alone won more medals than all but seven countries in the world. 🥇🥈🥉

Athletes from four California universities won 89 Olympic medals. (The United States won 126 total).

Athletes from Stanford University alone won more medals than all but seven countries in the world.

🥇🥈🥉
David Fajgenbaum, MD (@davidfajgenbaum) 's Twitter Profile Photo

What does Nobel Prize Winner Dr. Drew Weissman think of drug repurposing? Like us, he thinks it’s a no brainer! Developing new treatments for diseases is costly, time-consuming and driven by profit. Novel drug development requires $1-2B and 10-15 years per drug, and has a 90%

Samuel Hume (@samuelbhume) 's Twitter Profile Photo

The FDA approved 7 new drugs in June/July - what were they? 🧵 1. Donanemab, an antibody which clears amyloid plaque and slowed clinical progression of early Alzheimer's in a clinical trial:

The FDA approved 7 new drugs in June/July - what were they? 🧵

1. Donanemab, an antibody which clears amyloid plaque and slowed clinical progression of early Alzheimer's in a clinical trial:
Eric Topol (@erictopol) 's Twitter Profile Photo

It's one thing to have a cell atlas of the human body. It's another to build foundation #AI models, test perturbations, and establish causal effects. An insightful review/perspective Cell cell.com/cell/fulltext/… Jenny Rood, Ph.D. Anna Hupalowska Aviv Regev Genentech

It's one thing to have a cell atlas of the human body.
It's another to build foundation #AI models, test perturbations, and establish causal effects.
An insightful review/perspective <a href="/CellCellPress/">Cell</a> 
cell.com/cell/fulltext/… <a href="/jennyErood/">Jenny Rood, Ph.D.</a> <a href="/GraphicAnja/">Anna Hupalowska</a> Aviv Regev <a href="/genentech/">Genentech</a>
David Fajgenbaum, MD (@davidfajgenbaum) 's Twitter Profile Photo

Incredible results signaling that GLP-1s may be able to reduce mortality across a number of different diseases including as many as 10 different cancers… wow! We love repurposing drugs for add’l diseases they can treat. GLP-1s might overtake rituximab as the most repurposed txs.

David Fajgenbaum, MD (@davidfajgenbaum) 's Twitter Profile Photo

When a drug receives FDA approval, its research and development (R&D) often shifts away from further exploration into new indications. It's a common misconception that approval marks the peak of a drug's journey. In reality, it’s the opposite. When the drug eventually turns

Eric Topol (@erictopol) 's Twitter Profile Photo

Just published nature How fibrin drives brain inflammation in acute and #LongCovid and that a monoclonal antibody to fibrin protects against microglial activation nature.com/articles/s4158… Katerina Akassoglou Gladstone Institutes

Just published <a href="/Nature/">nature</a> 
How fibrin drives brain inflammation in acute and #LongCovid and that a monoclonal antibody to fibrin protects against microglial activation
nature.com/articles/s4158…
<a href="/AkassoglouLab/">Katerina Akassoglou</a> <a href="/GladstoneInst/">Gladstone Institutes</a>
Dr Steven Quay (@quay_dr) 's Twitter Profile Photo

An absolutely remarkable #Covid paper from UCSF. What did they find? 1. Fibrin binds spike protein 2. Forms proinflammatory blood clots 3. Clots drive systemic thromboinflammation & brain pathology, including #LongCovid 4. NK cell loss is seen & explains increase in #cancer

An absolutely remarkable #Covid paper from UCSF.

What did they find?

1. Fibrin binds spike protein
2. Forms proinflammatory blood clots
3. Clots drive systemic thromboinflammation &amp; brain pathology, including #LongCovid  
4. NK cell loss is seen &amp; explains increase in #cancer