Excited to share our new platform for hyperplexed IF spatial imaging & analysis - HIFI!

We developed this to be as #accessible & economical as possible for all interested in #spatial analysis of complex tissues

nature.com/articles/s4146…
#OpenAccess : rdcu.be/dELus

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An anniversary review on the Hallmarks of #cancer as a systemic disease, now Cell.
An effort led by Charles Swanton Elsa Bernard and written together with many wonderful colleagues.

authors.elsevier.com/c/1iqgjL7PXqPxO

So so happy to share our latest lab paper in Nature Communications dissecting the influence of oncogenic pathways on immune cell shaping in #HCC ! A 🧵 doi.org/10.1038/s41467… 1/n

Women are under-represented at senior levels in #academia globally, and across all #science disciplines, as shown by these 'scissor-shaped curves' ✂️

So how can we achieve #gender #equality ?

We discuss various strategies in this #Cell Commentary.. 🧵

cell.com/cell/fulltext/…

Huge congratulations to Turan Tufan for defining how macrophages use pause/release to rapidly (within min) modify their gene and protein expression during efferocytosis to ingest successive corpses! Thanks to many coauthors who helped us along! rdcu.be/dA6JJ

We found that chronic stress increases metastasis in mice. The neutrophils are at the helm (again!). Link to our report in Cancer Cell: authors.elsevier.com/a/1ieO05TA51hO…

This weekend, we celebrate the International Day of Women and Girls in Science!

What a privilege it has been to work with these extraordinary women Johanna Joyce Lab, all making an incredible impact in the world - in so many different ways!

joycelab.org/alumni

#WomenInScienceDay

Super excited to be here in #Banff for the Keystone Symposia 'Myeloid Cell Diversity: Fundamental Biology to Disease States'! Looking forward for my session and for the fantastic presentations and posters!

A final reminder for those of you attending Keystone Symposia “Myeloid Cell Diversity: Fundamental Biology to Disease States”: pack your bags with curiosity and excitement to share your science.

Safe travels and see y'all in #Banff in a couple of days!

Daniela Quail Lab Lai Guan NG

Thank you for highlighting our paper!

Great study dissecting mechanisms and targetable differences between minimally invasive and highly invasive brain metastases, by a wonderful group of colleagues Rosalind & Morris Goodman Cancer Institute Matt Dankner Sarah Maritan Peter Siegel and others - great work guys!! Tweetorial and link here👇

🚨 for all the neutrophiles out there: Perfect reading material for the plane this weekend to Keystone Symposia “Myeloid Cell Diversity: Fundamental Biology to Disease States” - Congrats Andrés Hidalgo and team!

Proud to share something we've been working on for a long time! andrew_dunbar Ross Levine Modeling oncogene-dependency using two recombinases Cre/Dre, comparison to Type II JAK2 inhibitors and sequential models of clonal hematopoiesis to MPN. More to come, check it out!

Thrilled our study on #brain #metastasis #vasculature is out Cancer Cell!!

Integrated analyses of human & mouse tumors revealed immune-regulatory pathways in endothelial & mural cells for therapeutic blockade

Led by the amazing Leire Bejarano 🤩

cell.com/cancer-cell/fu…

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Humbled by the congratulations received on our paper. It's a collective success, surreal to see it trending on PubMed. Thanks to my team and all collaborators!

Thanks LisaCoussens@CoussensLab! 10 women in STEM -pick it up and keep it moving Leila Akkari Casanova Acebes Lab The SchietiLab Jennifer Wargo MD Morgan Craig | Quantitative Medicine Lab Ashi_W Dr. Shruti Naik Karuna Ganesh Anna Obenauf Diletta Di Mitri Can I list more??? 🤩

Please take a min to vote for our study here!! Our work used AI to predict recurrence in early stage lung cancer patients from #IMC data, with goal of developing new ways to help guide clinical decision making.

I am so proud of my dear friend Lai Guan NG and his amazing team led by Melissa Ng

Science Magazine today, they show that tumors 'bend' the biological program of neutrophils regardless of their maturation state, in a deterministic manner, to produce vessel-building neutrophils

Proud and excited to finally share the entirety of our work, newly online in Science Magazine! Here, we reveal the deterministic reprogramming of pro-angiogenic neutrophils in tumours! #ThePowerOfMany #ScienceResearch

science.org/doi/10.1126/sc…
Read on to learn more! 🧵(1/16)

With 2023 behind us we're looking to expand the team with a postdoc position available! Our work spans patient sample guided-single cell genomics and mouse models of leukemia evolution. Lots of exciting work to be done. Formal job ad to follow, DM if interested!