Dan Western presenting his very large CSF pQTL analyses identifying more than 3,000 association, most novel. He integrated the pQTL data to identify 42 causal and druggable targets for #Alzheimers . #ADPD2023

Great resource from the Carlos Cruchaga lab & NGI Center highlighting the research of many people, including myself!

Great representation from the lab #ASHG2023 ASHG. Largest Early Onset #Alzheimer GWAS, and a lot of data from our multi-tissue, multi-omics QTL in diverse populations and its applications to complex traits by J. Bradley, Dan Western , Ciyang Wang and Chengran Yang

We leverage human multi-omic data to identify causal and druggable targets and to create novel predictive models for #Alzheimers . Come to use the four talks and four posters at the #AAIC24. neurogenomics.wustl.edu/the-neurogenom…. @WUADRC NeuroGenomics and Informatics Center WashU Medicine Neurology

Great work by Yuanyuan"Daisy" Shen and many others to characterize the early protein changes in autosomal dominant AD. So glad I could play a part in a wonderful publication!

I'd like to share our new lab publication Carlos Cruchaga on an atlas of CSF and brain metabolite quantitative trait loci. Special thanks to the mentorship of Carlos, and the instrumental contributions from both Chengran Yang and Dan Western. nature.com/articles/s4158…

Integrating GWAS and protein quantitative trait loci, scientists link 38 proteins to Alzheimer’s, 24 of them new. @WUSTL Nature Genetics Carlos Cruchaga ow.ly/hX7O50UoJTE