Competence in #Streptococcus controls genetic transformation, biofilm formation & virulence. Jan-Willem Veening &co show that it's also crucial for host #adherence, involving the fratricin CbpD, which exposes #virulence factors to the cell surface #PLOSBiology plos.io/3DtTwmJ

Missed this one from December but lovely looking structure. Passing resemblance to S.pneumoniae PcsB anyone? FtsEX-independent control of RipA-mediated cell separation in Corynebacteriales | PNAS pnas.org/doi/10.1073/pn…

Site-2-proteases trigger signaling cascades in response to external stimuli – as we learn more about them in different bacteria, they are emerging as #virulence regulators and targets for therapeutics. Read the review by Kristensen et al Morten Kjos 📑 academic.oup.com/microlife/arti…

Fantastic transatlantic collaborative work between Filippo Mancia Jonathan Dworkin Phill Stansfeld Linda Columbus 🏳️‍🌈 @OliBClark featuring the collective talent of Rie Nygaard Chris LB Graham Meagan Belcher Dufrisne Chelsea Brown & several others..University of Warwick Columbia Vagelos College of Physicians & Surgeons nature.com/articles/s4146…

Genome-wide CRISPRi screens reveal the essentialome and determinants for susceptibility to dalbavancin in Staphylococcus aureus dlvr.it/SvSrnF

Tell me you have two teenagers without telling me

New insights into the Undecaprenol monophosphate recycling pathway of Streptococcus pneumoniae academic.oup.com/femsle/article…

Our latest work on cell division is out. FtsEX:RipC in M. tuberculosis presents unique features compared with G(-) as a surprising inclined arrangement. A nice joint effort with Luo Min and Chris Sham Labs at NUS against this nefarious pathogen. nature.com/articles/s4146…

Finally online: Dennis Wicke's paper on a strongly conserved bacterial protein that interacts with RNase P and modulates its activity in Bacillus subtilis! Uni Göttingen 🤝Philipps-Universität #moty Nucleic Acids Res academic.oup.com/nar/article/do…

Have a look at our new paper on the role of CozE proteins in S. aureus Maria Disen Barbuti Grangeasse Team @CamiloPerezC6H6 Jan-Willem Veening xue liu Daniel Straume @a_ducret

🔔Job alert! 🔔 We are looking for a postdoc/researcher interested in characterizing enzymes at the interface of microbial denitrification and lignocellulose degradation🔬 Come join our #ERCfunded team! jobbnorge.no/en/available-j…

Already available our review on the regulation of lytic machineries by FtsEX in bacterial division. In recent years, amazing structural information has been provided on this, nearly conserved, bacterial system. Hope you enjoy febs.onlinelibrary.wiley.com/doi/10.1002/18…

Marita Torrissen Mårli has studied competence in Strep dysgalactiae strains from bovines and humans - and found a method to make mutants using natural transformation! Daniel Straume Davide Porcellato @UniNMBU Great collaboration with Oddvar Oppegaard @medofak_uib. mSphere journals.asm.org/doi/10.1128/ms…

Check out our new publication in Biofilm Journal on bacteriocin-based prevention of biofilm formation on materials used in medical devices doi.org/10.1016/j.biof…

We found that pneumococci struggle to develop resistance to the cyclic lipopeptide viscosin. Exploring less toxic derivatives may unveil promising new antimicrobials. Morten Kjos Cathrine Arnason Bøe journals.asm.org/doi/10.1128/sp…

This has to be some kind of record...

CRISPRi-Tn-Seq! Great collaboration with @tvanop nature.com/articles/s4156…

Our paper on Characterization of VldE (Spr1875), a Pneumococcal Two-State l,d-Endopeptidase with a Four-Zinc Cluster in the Active Site is available. Great collaborative work with Daniel Straume, Grangeasse Team and Mobashery lab University of Notre Dame. Hope you enjoy pubs.acs.org/doi/10.1021/ac…

Kamala Harris told us exactly what was going to happen.

Proud to share my latest publication! 🧬 We uncovered how Streptococcus dysgalactiae protects itself from a competence-induced murein hydrolase, ScrM, via a Fem-transferase-like immunity factor 🦠🔐onlinelibrary.wiley.com/doi/abs/10.111…