cool video and all but is anyone actually building puppramin or do i need to pivot LEAHLabsInc?

in the 1900s, it was common to dream of the 21st century. when was the last time you heard talk of a 22nd century? it's like we don't believe we're going to make it anymore, but to endure, we MUST dream of futures worth suffering for. please, dare dream of a 22nd century.

BIG NEWS! Ashlee Vance just profiled the first parents with not one — but two— Orchid superbabies. This is just the beginning. Every child, genetically blessed from day one.

Plasmid-based reporter assays are the bedrock of regulatory genomics. But a basic question has gone unanswered for decades: Do chromatin architectures form on plasmids transfected into mammalian cells—and does it matter? We finally have answers. biorxiv.org/content/10.110…

e/acc isn’t a movement—it’s the recognition that stagnation is engineered and that acceleration is the only viable counterforce what Elon is doing with SpaceX isn’t about escaping Earth. it’s about creating conditions so demanding they force civilization to evolve it’s a weapon

Can we just get a scientific revolution yet? My latest for Pirate Wires

We don’t need to industrialize biology we need to biologize industry

Gray Tribe Techno-optimists Abundance Bros Let us all unite as the Technocratic Party

Called the vet within 3 minutes of getting an email that Loyal STAY study is finally enrolling in the Twin Cities. 🐶/acc

👋We’re excited to launch DSG2-mini, our newest AI protein design model, now available in DiffuseSandbox⏳🎁, our new app for protein binder design. Click through to design a protein yourself! diffusesandbox.com 1/

You may not like it, You may not understand it, but this is what the future of biology looks like. Another successful trial completed 🐶✅ for all pet/kind.

Scientists and founders who don’t go all in on AI will quickly be outcompeted by those who do. The dispersion will become obvious in a year. Once you see it, you realize there’s never been a better time to be a biotech builder.

do think discourse on engineering biology would benefit from fewer platitudes about the complexity of living systems and more informed optimism about our inevitable path to break down, understand and rebuild organisms

Now imagine a regulatory regime that would allow you to sequence -> design -> engineer -> dose an allogeneic therapy targeting multiple neoantigens (perhaps even multiple n of 1 neoantigens) in mere days.

Teach your children early about the chirality of the DNA double helix so that they can live their lives free of inaccurate DNA structure diagrams

🚨The Bits to Binders Competition has concluded!🧬 One year ago we gathered scientists from around the world to design and submit protein binders that cause immune cells to target and eliminate CD20+ tumors Spoiler: They work!

IN THIS HOUSE WE BELIEVE

Welcome to the age of generative genome design! In 1977, Sanger et al. sequenced the first genome—of phage ΦX174. Today, led by Samuel King, we report the first AI-generated genomes. Using ΦX174 as a template, we made novel, high-fitness phages with genome language models. 🧵

Today we’re launching Proteinbase, a single hub for experimental protein design data. Over 1,000 novel proteins are already live, each with computational predictions, experimental validation, and the method used to design them. Everything comes from one lab under standardized