We are excited to join the #Immune2Cancer Day. Spread awareness about the importance of lifesaving cancer immunotherapy research on #Immune2Cancer Day. Join Generation Cure. #CIM21 Cancer Research Institute

Sending our girl off to Harvard! We’ll miss you Ngima! 🧬🔬#cancerbiologists

Check out our newest review on TREM2 in tumor-associated macrophages by Darya Khantakova, Simone Brioschi (twitterless) and Martina Molgora mdpi.com/2076-393X/10/6…

Fun celebrating end of summer with these beautiful people - pool party! WashU Cancer Biology PhD Program

Congrats to our postdoc Patrick Rodrigues and Roxane tussiwand: Using multiple mouse lines, including the newly generated CD300c-Cre-hCD2, they showed that pDC-like cells, a subset sharing features with pDCs and cDCs, are circulating precursors with cDC2 potential!🎉 science.org/doi/10.1126/sc…

Congrats to Jinchao Hou (JinChao Hou) and Yun Chen. Our new study highlights the role of LILRB4 inhibition in enhancing microglial function and reducing amyloid-β accumulation, suggesting LILRB4 as a potential treatment target for AD. science.org/doi/epdf/10.11…

The combination of #TREM2 deficiency and #anti-PD1 #immunotherapy reprograms gut bacteria to support #tumor rejection in mice. The Colonna Lab Learn more: scim.ag/6ZZ

Excited to share our latest paper: combining anti–PD1 treatment with TREM2 deficiency in mice triggers a proinflammatory response in the gut, promoting the expansion of Ruminococcus gnavus. Congrats to first authors Blanda Di Luccia Martina Molgora Darya Khantakova doi.org/10.1126/sciimm…

Congrats Patrick Rodrigues! Distinct lineages contribute to cDC2 diversity: lymphoid-derived pDC-like and myeloid-derived pre-cDC2 both develop into transcriptionally similar cDC2, crucial for humoral immune responses, and are distinct from pro-DC3 derived DC3. twtr.to/Tr5-h

Excited to share that our work by Patrick Rodrigues and Tong Wu is published in Cell: RORγt+ DCs are required to induce oral tolerance. Their absence reduces pTregs and impairs oral tolerance to dietary antigens. Read more: authors.elsevier.com/sd/article/S00…