A new 2025 article by Dr. José Valerio in Brain Sciences shows us how the OR and clinic are about to get 'a lot smarter.' Will DBS and neuromodulation become so complex it will become inaccessible to most people around the world? Enter AI. Artificial intelligence or AI is no

Comprehensive systematic review and meta analysis by Dhaliwal et al on 49 DBS studies for epilepsy. Key points: 60-70% overall seizure reduction and responder rates for ANT/CMN targets. Strong support for long term benefits of DBS for epilepsy sciencedirect.com/science/articl…

Jin et al demonstrate a novel neuromodulation technique of hybrid upconversion and photovoltaic nanoparticles activated by near-infrared light. Is this the successor to optogenetics? Could this be translated to humans? Very exciting technology! science.org/doi/10.1126/sc…

The 3rd DBS Think Tank Rising Stars will take place on Aug 29, 2025 from 1pm to 3:30pm (Virtual only). We are looking to support the next generation of DBS junior scientists! Submission deadline July 1st! Submit your abstracts here fixel.ufhealth.org/think-tanks/de…

Ricciardi et al report an interesting effect of dual frequency (high+low) STN stim on verbal fluency in PD. The combination of high+low was better than either alone. Could this be a new paradigm for all STN DBS? Read more here …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…

Did Helicobacter pylori just break the amyloid code? Meet CagA which is nature’s unexpected anti-amyloid weapon! As a neurologist, I never thought I'd say this: a stomach bug may possibly hold a secret about modulating amyloid diseases like Alzheimer's. Zin and colleagues just

This is an amazing course and all movement disorders fellows should try to attend this if they can!

We are calling all junior scientists who are pioneering the next generation of knowledge in neuromodulation! The deadline to submit to the DBS Think Tank Rising Stars Challenge is next week! Get your abstracts in now! fixel.ufhealth.org/think-tanks/de…

This is a great resource for movement disorders education! Recommend everyone sign up for this and attend the amazing weekly lectures!

Can we reboot walking after Parkinson's disease DBS? Can AI teach deep brain stimulation devices to help people 'walk the walk?' A new study by Wang and colleagues in Nature Parkinson’s Disease says MAYBE. Using personalized data-driven models, researchers at UCSF have optimized

Today is the last day to submit your abstracts for the DBS Think Tank Rising Stars challenge! Enter for an opportunity to present your work to the DBS community and a seat at next year's Tank! fixel.ufhealth.org/think-tanks/de… fixel.ufhealth.org/think-tanks/de…

Great topic for journal club! Tune in if you can!

nature.com/articles/s4153… New study out npj Journals! Is bilateral STN #DBS for #ParkinsonsDisease merely 2 × unilateral—or something more? We scanned 22 patients with #BOLD #fMRI: half with one lead on, half with both. Bilateral stimulation showed a synergistic suppression of

This is a very interesting condition with complex phenomenology. DBS tends to work well but not always a straightforward post-operative path. Read about Dr Remz's experience with DYT-11 DBS troubleshooting here frontierspartnerships.org/journals/dysto…

Great review as non motor symptoms can be very challenging to treat whether it be pharmacologic therapy or DBS!

A report of 2 years worth of MRgFUS from a single center (n=108) demonstrating tremor suppression consistent with previous results. 82% had transient side effects but 33% had persistent gait issues at 12 months. Can we refine targeting further? …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…

Great take home message for management of early PD!

Great paper by Daniel G. Di Luca on the predictors of levodopa reduction after GPi DBS in PD. They found that anteromedial stim was associated with higher LEDD reduction. Bringing back the rematch to challenge the idea that GPi DBS has minimal med reduction. …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…

Dr. Currie highlights the essential role of social workers in DBS preoperative evaluations. While the medical team focuses on clinical aspects, social workers assess vital psychosocial components that might otherwise be overlooked …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…

New report by Donlon et al on GPi DBS for X-linked dystonia parkinsonism (DYT3) on 2 patients. Electrophysiologic characterization noted to vary with the phenotype but both responded to neuromodulation. Great videos too! …mentdisorders.onlinelibrary.wiley.com/doi/10.1002/md…