Excited to share my postdoc work on SARS-CoV-2 variants with John Briggs. Fun collaboration with Tom Peacock Jonathan Brown Imperial College London; Tristan Croll and Abhay Kotecha. The work started 3 years ago at the beginning of the Alpha variant @MRC_LMB and finished at Max Planck Institute of Biochemistry (MPIB)

Well, seems I’ll be attending #ccp4sw remotely this year. 😔

Virion morphology and on-virus spike protein structures of diverse SARS-CoV-2 variants. Preprint from Zunlong Ke in collaboration with Tom Peacock wendybarclay Abhay Kotecha Tristan Croll and others. biorxiv.org/content/10.110…

On a separate note, particularly for Mac users of ISOLDE: I’d highly recommend updating to ChimeraX 1.7.1. The 1.7 release inadvertently left out the faster Metal2-native OpenMM implementation, so updating should get you back up to speed.

I can do this in two seconds and tell you that the answer is epigallocatechin gallate

High-res In-situ Structures of Mammalian Respiratory Supercomplexes in Reaction within Native Mitochondria biorxiv.org/content/10.110… Check out my lab's first work on membrane proteins! Yes, we knew nothing about detergent😜, so we directly imaged proteins within native membrane!

🤦 All I wanted to do was test the new ISOLDE release, I swear! (in other news, I just uploaded new builds for ChimeraX 1.8. Enjoy!).

My daughter walks in and says, “every time I look at my school art project, it just gets worse…” We really are our own worst critics, aren’t we?

I'm getting

I'm sure there's a historical reason for it, but... *L-*dopamine??

From the number of notifications on my phone lately, I see there’s a mass exodus of scientific folks to the azure place. Guess it’s time for me to leave this place to the bots as well, but I’ll probably be quiet for a while. Current mood: