📢 We are on the lookout 👀 for a PhD candidate! Fully funded 4-year project focused on the molecular dynamics of replication stress sensing at the replisome core. Please RT 🙏🏻 !

📣New opportunity for #Postdoc researcher!📣 If you are interested in #telomeres and #genomestability, don’t miss this chance! Application details at gimm.pt/jobs/junior-re…. Feel free to DM or email us ([email protected]) for more info. Vacation code: IMM/CT/71-2024

1/ 🤔 Do #chromatinlooping-mediated promoter-#enhancer interactions drive gene expression? Or is the local enrichment of transcription factors into hubs/#condensates the key factor? Our AC/DC model of gene regulation at bioRxiv doi.org/10.1101/2024.0… provides a new view on this.

Wonderful resources.

Having a hard time with #CRISPR HDR? Your cells might be fighting against you! TREX1 nuclease, high in some cells, eats up HDR donor templates. Check out our paper in Nature Biotechnology for the story & ways to improve HDR. nature.com/articles/s4158… With Erman KARASU & John Maciejowski

A new paper from Lauberth Lab by Mannan Bhola and Kouki Abe shows how RNA and TOP1 work together to regulate DNA topological stress during transcription Molecular Cell. It was a pleasure working with the Mondragon, Eric Van Nostrand , John F Marko , and He labs. authors.elsevier.com/a/1jd-m3vVUPRm…

Mark your calendars! Zoom link coming soon.

Transcriptional deregulation at the basis of multiple sclerosis! We feel privileged for the opportunity to add our small contribution to this impressive piece work. A pleasure to collaborate with such great scientists

An exciting meeting with lots of exciting results and interesting discussions. Thanks everyone for such a great time!

Gracias a CaixaResearch por el apoyo! Junto con Rafa F Leiro intentaremos llevar el potencial diagnóstico de los sistemas CRISPR-Cas al siguiente nivel, suministrando información genética directamente al paciente y acelerando la toma de decisiones clínicas CNIO Stop Cancer

Very excited with this project in collaboration with Rafa F Leiro, and grateful to CaixaResearch for the support in this amazing program #CaixaImpulse

Fundación ”la Caixa” Fundação "la Caixa" Agostinho Carvalho Coral Barbas Manel Esteller Vall d'Hebron Institut de Recerca Catalan Institute of Nanoscience & Nanotechnology Universitat de Barcelona @CIBERBBN Patricia Maciel Maria Pia Cosma Endocrine Regulatory Genomics Lab Heiko Lickert Guadalupe Sabio @MariaJ_Alonso m.gimenez-marques Antonio Vidal-Puig Manuel Romero-Gómez 16/ 🏆Llegamos al ecuador de la ceremonia con los 6 reconocimientos en oncología, entregados por: 🔵 Juan Ramón Fuertes, director general adjunto Fundación ”la Caixa” 🔵 Ignasi López, director del Área de Relaciones con Instituciones de Investigación y Salud Fundación ”la Caixa”

Many thanks to Fundación ”la Caixa” CaixaResearch for the incredible support to work on this important problem together with Borja Ibarra Borja Ibarra and Cristina Ugalde Postdoc positions will be opening soon! Exciting times ahead!

Cuatro investigadores del #CNIOStopCancer reciben financiación CaixaResearch. cnio.es/noticias/cuatr…

CaixaResearch Cortés Lab Guadalupe Sabio Rafa F Leiro Llorca lab En este hilo de CaixaResearch puedes ver cómo fue la ceremonia y conocer a los demás investigadores e investigadoras homenajeados. Enhorabuena a todos.👏 x.com/CaixaResearch/…

Very excited with the opportunity to take our basic discoveries on DNA topology and topoisomerase function to possible applications in our fight against cancer with this #CaixaResearch grant Thanks CaixaResearch! Opportunities to join this project CNIO Stop Cancer will follow

En nuestro grupo en Cabimer investigamos sobre el síndrome por deficiencia en el gen CHD8. Buscamos a personas diagnosticadas con alteraciones en este gen, para asociarnos, intercambiar experiencias y aumentar el conocimiento sobre el síndrome.👇👇

Have a look at our review in Molecular Cell . We explore how histone modifications serve as integrators of genome activity, mediating communication between distinct DNA procesess. authors.elsevier.com/a/1kS2f3vVUPRn…