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Excited to share my Rabinowitz lab postdoc work on glycine & serine! Metabolomics & tracing show SHMT is a net consumer (not producer!) of whole-body glycine. Homeostasis is by tuning this consumption to dietary levels without change in de novo synthesis biorxiv.org/content/10.110…

Happy to welcome the lab’s second postdoc AND The University of Chicago’s first IRACDA fellow Kevin Muñoz Forti!

Congrats to DR Juan José Apiz Saab (he/him) for successfully defending his UChicago Committee on Cancer Biology thesis!

Elegant talk by Dr Alex Muir Muir Lab on nutrient stress in #pancreaticcancer microenvironment and how it affects chemoresistance and other cancer cell biology. PanCAN funded Alex and now funding Fellowship for his postdoc Dr Cognet. #AACRpan23

Allison Rosenzweig PanCAN Thanks Allison Rosenzweig! Grace Croley Colin Sheehan Guillaume Cognet having been doing great work, excited to share it! HUGE thank you to everyone at PanCAN for supporting our first studies on nutrient stress and Guillaume Cognet as he takes this work further!

Laura LAUTURE CRCT-Oncopole Cellules leucémiques et métabolisme : quand la résistance thérapeutique s’en mêle ! Son étude se penche sur un processus à la fois essentiel et complexe : le métabolisme énergétique des cellules leucémiques.

Really happy to share with you that I have successfully defended my PhD last week 👩🏼‍🔬🎓🎉! Many thanks to my PhD director Jérôme Torrisani and all my amazing colleagues, friends and family 💐🧡

It was a blast to spend one week in Chicago with Brandon Faubert’s team. Thank you, @Brandon_Faubert for showing me the best of isotope tracing and metabolic flux analysis. Thanks, guys, for the warm welcome. Happy to be on the dark side of flux.

#cellbio2023 interested in metabolism and cancer? check out Guillaume Cognet talk on how small amino acids like glycine make cancer cells chemoresistant this afternoon at 4:30 in the very cool Concepts in Signaling and Metabolism session! Excited to see all these talks!

#cellbio2023 Interested in cellular lipid metabolism and how the tumor microenvironment impacts lipid metabolism? Check out Patrick Jonker talk tonight at 5:45 in the Cellular Mechanisms of Transformation, Dormancy and Resistance session. Looking forward to the whole session!

I beyond honored to have won the Dermato Oncology award of the ADF - Arbeitsgemeinschaft Dermatologische Forschung #ADF Thanks Aslan Tasdogan and team for making this possible #melanomaresearch

Huge congratulations to Alexander Muir, PhD, on receiving #NCCN foundation #YoungInvestigatorAward for his outstanding potential contributions to the cancer treatment delivery landscape. #PancreaticCancer National Comprehensive Cancer Network (NCCN) UChicagoCancerCenter UChicago Committee on Cancer Biology ow.ly/iq5950RgglA

For the love of God people just do some experiments, enough with the single cell seq atlases

The phrase ‘metastasis accounts for 90% of cancer deaths’ is one of the most widely used in cancer research, yet it is overly simplistic, imprecise, and it is difficult to find any primary analysis supporting the statement. | → rdcu.be/dLgsZ ← | 🧵(1/5)

Hi #metabolism twitter. ~5 years ago wrote a review with MVH Lab and DMM Journal about how the microenvironment drives many metabolic features/targets of cancers: tinyurl.com/3sk263z9 1/7

Check out Alex and I’s latest review! I’m proud of how this came together and excited for the future of the field of lipid metabolism in the tumor microenvironment!

Awesome presentation by Guillaume Cognet Guillaume Cognet from the Muir Lab The University of Chicago on the role of amino acids in tumors and their impact on chemotherapy outcomes. #MidwestMetabolismMeeting

Hi #cancer #metabolism twitter. New review from Guillaume Cognet: science.org/doi/10.1126/sc…. Has long been understood that tumors experience metabolic stress due to nutrient limitation in the tumor microenvironment. 1/7

Hi #metabolism #pancreaticcancer #lipidtime twitter! Excited to share Patrick Jonker work on how the microenvironment limits the metabolic capacity of pancreatic cancers (PDAC), which sensitizes these tumors to dietary interventions. 1/17

Check out the first portion of my PhD work in the Muir Lab! Super excited to see this out. Huge thanks to everyone who helped out. Let us know what you think!!