We identified a complex network of proteins that regulate MMEJ:NHEJ repair pathway balance in a chromatin context-dependent manner. With impact on cancer genomes. Paper is finally out: nature.com/articles/s4146…

... and we used our platform of 19 chromatin-integrated pathway reporters to probe context-dependent effects of epigenetic drugs on Cas9 editing: academic.oup.com/nar/advance-ar…

Wat een knappe prestatie! Super dat deze leerlingen zo goed scoren op de internationale biologie-olympiade. Van harte gefeliciteerd! 🎉 biologieolympiade.nl/2024/nederland…

The first story of my PhD is now available as pre-print: biorxiv.org/content/10.110…. We used highly multiplexed local reporter hopping to map the functional landscape of the Sox2 locus. My colleague, friend & co-author Mathias Eder summarized the highlights for you:

Did you ever wonder how transcription initiation compares between flies and mammals? The project that started as my master thesis in @arnaud_kr lab, was continued by @KCTattwo is now out on BioRXiv: biorxiv.org/content/10.110…. Read his summary below: