My main PhD work is now out as a preprint 👇

This Thursday, an afternoon of discussion about how knowledge of developmental mechanisms can inform us about disease.

Staring at the Sun - researchers have never before had such detailed views of our nearest star Read the full story: nature.com/articles/d4158… This gif shows a snake-like disturbance of relatively cool plasma rippling across the Sun

Interesting idea, especially coupled to the knowledge that histones and DNA also can act as a major sink for intermediary metabolites.

🏅We're delighted to announce Dr Matthew Higgs as the winner of the 2023/24 Bruce Cattanach Prize. Funded by Mouse News Letter Ltd, this prize is awarded annually for an outstanding PhD thesis related to the use of non-human in vivo animal models genetics.org.uk/8-november-202…

Much needed artist protection or the end of technology as Frank Herbert predicted? technologyreview.com/2023/10/23/108…

Fantastic story about how a primate-specific trancription factor regulates repetitive sequences that control embryonic pancreas fate.

Very happy to see our last paper of 2023 is out: The loci of many genes with redundant function (including paralogs) are in close proximity in 3D #Chromatin_loops. We show that such gene-gene loops often involve genes that cross-regulate each other’s expression. 1/4

The prevalence of suboptimal affinity binding sites within enhancers creates a vulnerability in genomes whereby single-nucleotide changes that optimize affinity, even slightly, can be pathogenic. doi.org/10.1038/s41586…

Interested in women’s health? Looking to undertake a MSc? Then look no further! Our MSc in women and children’s health covers key topics in reproductive and maternal health, pregnancy, and infant health using novel teaching and assessment approaches kcl.ac.uk/study/postgrad…

Weight gain during nutritional rehabilitation post-childhood malnutrition may influence the associations between adulthood desaturases activity and anthro-cardiometabolic risk factors sciencedirect.com/science/articl…

Congratulations to our amazing Dr Lillina Vignola for her successful thesis defence yesterday!

More good news from the lab! Felicitations to the fabulous Risha Amarsi who successfully passed her PhD viva last night.

We have two new faculty opportunities at QMUL, part of a £3.2M investment by Barts Charity to develop genomic and epigenomic liquid biopsy analyses for diagnostics and research applications. More details here: qmulepigenetics.com/jobs Please RT abundantly

We are really pleased to share our new paper where we show that Liver X receptor signalling in the mother is a key event in the transport of essential long-chain polyunsaturated fatty acids to the fetus. With Risha Amarsi Dr Samuel Furse Albert Koulman nature.com/articles/s4146…

Have you heard of ‘pregnancy brain’? Recent research shows that changes in the brain with #pregnancy correlate with successful bonding to the infant! See: nature.com/articles/d4158… Created with support from Cambridge University Public Engagement and British Society for Immunology 🙏🏻 #whum #womenshealth

🚨Thrilled to share our latest preprint on #MammaryGland development during pregnancy and #lactation, using 480 transcriptomes to map allelic gene expression over 10 key stages! 🧬🍼 Check it out: biorxiv.org/content/10.110… 🧵👇

Looking for a PhD? Interested in epigenetics, imprinting and transposons? Come join the Jennifer Frost and RJ Oakey labs for our project in the 2025 KCL MRC DTP scheme, applications are now open! Link to project: kcl-mrcdtp.com/project/the-ro… King's College London Media Research Center #MRCDTP25

PhD position open in my lab The Francis Crick Institute - more info here: crick.ac.uk/careers-study/…

Our latest preprint. @L_Lampe, clarenewell and colleagues figured out how metamorphosing #Drosophila avoid drying out. The larva makes a lipid barrier of hyper-long hydrocarbons (>C27 and longer) and stores it in the fat body until needed by the pupa. tinyurl.com/3keukxsz