Check out Vikram Vijayan’s exciting work showing evidence of integration in a neural circuit! Very happy that I could be a part of this project

From our preprint! The fly walks on a 3D-printed treadmill with different substrates while simultaneously being imaged via two photon microscopy. We’ve found a rise to threshold in oviDNs related to the relative value of the substrate. At threshold, an egg is laid.

2nd preprint describing the egg laying behavior and decision making in more detail!

Paper is out! #Drosophila 'know' what's best! Flies build an internal expectation of the substrate options in their environment and use it to make informed egg-laying decisions. science.org/doi/10.1126/sc… [fly exploring options before laying an egg on the best one, 20x speed]🧵(1/7)

How do tissues generate diverse cell types in defined proportions that vary across space and evolution? Our new preprint presents Lineage Motif Analysis (LMA), a statistical approach that extracts generative fate programs from observations of cell fates on lineage trees. /1

Some work during my time at Rockefeller showing how fruit flies navigate decision making! Finally out in nature.

Released my preprint! Here, we leverage spatial information to resolve temporal dynamics in male germ cell development! We reveal that Sertoli cells are precisely synchronized with periodic germ cell development and have an innate cyclic program independent of the germ cells!

Our hotel also didn’t have any alternatives 🤦

Excited to give a talk at Winter Q-Bio this Tuesday, 2/18 during session 1! I’ll be discussing our work using spatial transcriptomics to resolve temporal dynamics in the seminiferous epithelial cycle. Come say hello and chat science!

Check out what I’ve been up to for the past four years at Caltech! Exciting road ahead for therapeutic circuits.