The Tufts Biology Research Club Tufts Biology Department hosted a successful undergraduate research symposium today. Congrats to organizers Lema Abuoquab and Ze’ev Drukker for pulling it off! Katie Kean Tufts Biology Department ambassador presents her poster

Great work from the David Cortez lab! doi.org/10.1126/scienc…

Thanks Vincent! It was surprising how exposing a (CTG)70 repeat within a gap created a super-fragile site. And that gap repair driven expansions are highly dependent on which sequence is the template for gap repair.

Hot of the press in NAR Cancer. Culmination of many years of effort, Divya's PhD, the project started by @science_SRH while in my lab, and a wonderful collaboration with Ashley Spies' and Pietro Pichierri 🇮🇹🇪🇺 @[email protected] labs Check out our new, drug-like RAD52 inhibitors academic.oup.com/narcancer/arti…

Kudos to postdoctoral fellow Erica Polleys for establishing this system to study repeat instability during gap repair. And for her discovery that DNA structures within gaps create a super fragile site!

Got old #yeast? Zhou et al rewire #transcriptional death pathway switch away from typical #nucleolar or #mitochondrial decline to delay #aging via negative-feedback loop, increasing life span by 82% yeastgenome.org/reference/S000… Science Magazine Long live yeast!

We're looking for a Research Assistant to develop better #AAV constructs for #Crispr Cas9 expression for #GeneEditing in vitro and, eventually, in the brain. Join a vibrant group of people at the UK Dementia Research Institute at Cardiff! Closes May 14th! apply here: tinyurl.com/2p8bmcdw

Register now for #yeast2023! Submit abstract by May26, Early bird registration by May31! Get your summer dose of yeast #genetics in Tuscany 🌞 yeastflorence2023.com

Great to see 4 awesome women scientists doing such important service for the community!

Three of the more costly and frequently used reagents in molecular biology are rolling circle amplification (RCA) mix, chemically competent MachOne (or other E. coli) cells, and Gibson assembly mix. Postdoc Julian Willis—who is starting his own lab in the UK soon—developed

A nice read! Thanks for writing such a clear summary on the danger of DNA structures exposed within gaps.

You are a real Jumbo now Sarah. Playing softball with Tufts Biology Department and the librarians!

If you found this thread helpful and would like to know how to develop your paper so that it is well structured and tells a consistent story, here is a free training for you: 👩‍💻👇 annaclemens.com/training?utm_s…

#1 Happy to share our work “Specialized replication mechanisms maintain genome stability at human centromeres” Molecular Cell from A. Scelfo, A. Angrisani and T. Wilhelm Institut Curie CNRS 🌍 where we provide the causes of centromere fragility. authors.elsevier.com/a/1iba63vVUPRl…

Our new manuscript is online! Cas9 nickase-mediated contraction of CAG/CTG repeats at multiple disease loci biorxiv.org/content/10.110… Giant team effort! Led by the incredible Alvaro Murillo with more help from Mariah Lelos, DAVIDSON LAB, and many many more. Here's a thread.

I had the pleasure of watching this story develop. An important contribution to the repeat field!

Got this very cute present from former postdoctoral fellow Erica Polleys @EricaJeanPhD who contributed so much to my lab’s research. Made by a former grad student in our department who sells great science stuff on Etsy

Tufts Bio’s Mitch McVey and his merry band of scientists made some new data — check it out!

🚨🚨🚨We’re excited to give a Jumbo welcome to Khoa Tran, who’s joining Tufts Bio as an Asst Prof in Sept’25! Learn about Khoa and his research on metabolic-epigenetic crosstalk here: khoaatran.com/research

A very cool paper about how the human Shu complex regulates recombination with potential implications for cancer therapy. Congrats to first author Sarah Hengel and all coauthors for this important scientific advance!