
CaldasLab
@caldaslab
Functional genomics of breast cancer lab based at the University of Cambridge
ID: 1232350484251512832
https://www.cruk.cam.ac.uk/research-groups/caldas-group 25-02-2020 17:08:04
569 Tweet
809 Followers
273 Following

@caldaslab is excited by this important tool and its deployment to help unravel spatial biology! Mor Nitzan continues to show us the way towards computing tissue organisation! nature.com/articles/s4358β¦


This is a seminal review! Metabolic factors in both micro and macro environment of cancers play a major role in tumor biology and therapy response! Bluring of fields! Joining Inst Metabolic Science-Metabolic Research Labs has a reason!

Thrilled and proud to be part of the Rueda Lab! This is a huge achievement for Oscar M Rueda and the entire team. Excited to see the outstanding results from this groundbreaking research initiative! MRC Biostatistics Unit #CancerResearch #AI #MachineLearning π

Amazing news to the MRC Biostatistics Unit & Oscar M Rueda Lab! Congrats!

A pleasure to host the QBS today! What a fantastic seminar we had at CRUK Cambridge Institute given by Jeffrey West ! Very interesting data and models you presented! Hope to have you in Cambridge soon again!



π’Our work just published in Nature Communications Nature Portfolio! What is driving #response to #targeted #treatments in HER2+ER+ #breastcancer? How is the tumour ecosystem affected by treatment? Find the answers in our paper π rdcu.be/ecbVR Key points below π


Beautiful work Maurizio Callari ! Contras to you and the team!

#StandUpForScience Not posting much on Twitter these days, but this one worth it. Seen at the rally near UCLA campus Donald J. Trump


Here an overview of our #translational research on samples from #NAPHER2 trial recently published in Nature Communications. We identified #predictive #biomarkers and molecular dynamics in HER2+ER+ #breastcancer receiving chemo-free #targeted #treatment π

Submitted our new paper to nature which will undergo traditional closed review by volunteer reviewers, posted preprint to Research Square for all to see, shared on ResearchHub for preprint to be reviewed publicly. Our reviewers ResearchHub will be paid and those reviews will


Excited to share our latest work on monitoring response to treatment using ctDNA and shallow WGS using a Bayesian Model developed by Solon Karapanagiotis with Carlos Caldas π΅πΉπͺπΊπ¬π§π, Emma Beddowes and Mario Ortega febs.onlinelibrary.wiley.com/doi/10.1002/18β¦

Serial shallow copy number profiling from ctDNA predicts breast cancer treatment response and survival! All made possible by a novel Bayesian machine learning model developed by Solon Karapanagiotis and Oscar M Rueda, and the years long efforts of Emma and Mario during their time CaldasLab

Super happy to see this out! π A nice piece of work I contributed to during my time in Cambridge. It highlights the potential of liquid biopsy paired with advanced statistical modelling! Well done Oscar M Rueda Solon Karapanagiotis and co!!

π§¬π»A large-scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression-free survival π buff.ly/jWEEbZi Stephen John Sammut #BCSM #CancerAI #ctDNA



Such a beautiful project and a pleasure to work with NguyenLab.bsky.social ! Please share and post our recent work Cell cell.com/cell-reports/fβ¦ from the CaldasLab Carlos Caldas π΅πΉπͺπΊπ¬π§π and Oscar M Rueda ! See the complete story in bluesky bsky.app/profile/nguyenβ¦ by Long