Adenosine-to-inosine RNA editing by ADARs, first discovered in the 1980s, plays a complex role in disease. This #RNASpecialIssue review explores current knowledge, therapeutic potential, and key unanswered questions. bit.ly/3F3Vqy1

This Perspective from the #RNASpecialIssue summarizes the current knowledge of translation dysregulation in cancer, with emphasis on the eukaryotic translation initiation factor 4F complex. It outlines recent endeavors to develop novel treatment strategies to combat cancer:

Our review epub CSHLPress. Great ride led by Luis Batista WashU Medicine Division of Hematology & by @CEI-FCCC Fox Chase Cancer Center contributing to an understanding of telomerase RNP - the immortality enzyme hijacked by 85% cancers and the untapped "fountain of youth" for aging diseases.

Connecting genotype and phenotype in minor spliceosome diseases. This article from the #RNASpecialIssue outlines the current structural and functional knowledge of the minor spliceosome, and discusses emerging challenges in connecting molecular dysfunctions to clinical

SPECIAL ISSUE Part 2! This month Genome Research publishes a diverse collection of articles offering novel biological and clinical insights gained using long-read DNA and RNA sequencing technologies and other long molecule approaches. tinyurl.com/Genome-Res-35-4

RNA-binding proteins at the crossroads of disease: Fragile X Syndrome and Spinal Muscular Atrophy. Discoveries of the SMN complex and its unanticipated function in RNP assembly, essential for spliceosomal snRNP biogenesis, advanced understanding of RNA biology and pathogenesis.

SF3B1: from core splicing factor to oncogenic driver. This article from the #RNASpecialIssue discusses how specific transcripts affected by aberrant splicing in SF3B1-mutant cells contribute to the initiation and progression of cancer. It also highlights the prognostic value and

📽️ G&D Tapes 📽️ G&D author, Jelani Lyda talks about a new study in #GenesDev by Riley et al. reporting the role of ClpCP protease and novel protein MdfA in driving metabolic differentiation and dormancy during bacterial sporulation. Learn more here: ➡️ tinyurl.com/gd352535

NEW ISSUE ALERT!!! Check out the new Research Papers, Review, Perspective and Outlook Articles online now at Genes & Development. Click on the link for more: ➡️ genesdev.cshlp.org/content/current

The new issue of Genome Research is now live! Follow the link to a new ultra-long nanopore sequencing toolkit, a unified analysis of atlas single-cell data, and more! tinyurl.com/Genome-Res-35-5

Call for Papers! Genome Research is now encouraging submissions for a Special Issue on The Genetics and Genomics of Somatic Mosaicism, Guest Edited by Drs. Gilad Evrony, Eunjung Alice Lee, and Raheleh Rahbari. tinyurl.com/Call-for-paper… #BOG25 #KSMosaicism25 #MITS25 #somaticmosaicism

The new issue of Genome Research is now live. Follow the link to new research on TP53 regulation of transposable elements in cancer, gut microbiome–associated protists, and more! tinyurl.com/Genome-Res-35-6

The new issue of Genome Research is now live. Follow the link to new research on single-cell multiomics of muscle response to endurance exercise, a method for Nanopore data compression, and more! tinyurl.com/Genome-Res-35-7

NEW ISSUE ALERT!!! Inspired by the 2025 CSHL Symposium on Aging & Senescence, this issue features a collection of Outlook, Perspective, and Review articles on the impact of aging on metabolism, immunity, reproductive health & cancer. Online now: ➡️ genesdev.cshlp.org/content/39/15-…

The new issue of Genome Research is now live. Follow the link to new research on oxygen stress and gene regulation in the brain, a new C. elegans reference genome, and more! tinyurl.com/Genome-Res-35-8

The new issue of Genome Research is now live. Follow the link to new research on HER2 isoform diversity and drug resistance in breast cancer, off-target site detection in prime editing, and more! tinyurl.com/Genome-Res-35-9

🚨 NEW ISSUE ALERT!!! 🚨 New Outlook, Review and Research Papers online now at Genes & Development. Click on the link to learn more: ➡️ genesdev.cshlp.org/content/39/19-…

The new issue of Genome Research is now live. Follow the link to new research on microglia in neurodegenerative diseases, intron retention in nuclear RNA complexes, and more! tinyurl.com/Genome-Res-35-…

Coming Soon: 'Epigenetics: History, Molecules, and Diseases' by John Greally. A clear-eyed, provocative journey through one of biology’s most captivating and misunderstood ideas. Available in print, eBook, and Kindle formats Tuesday, October 21.

Now Available! “Epigenetics: History, Molecules, and Diseases” cuts through hype to trace the field from its origins to today’s genomic landscape. A clear, authoritative guide to what epigenetics is—and is not. Now in print + eBook formats: bit.ly/epigeneticsbook