'We must thus continue to advocate for clinical trials to evaluate efficacy of medications for stone prevention.' This Editorial discusses a recent study found treatment with one or more stone-related medications was associated with fewer stone events bit.ly/CJASN0459

New insights suggest that central body fat distribution might provide power in assessing kidney risk. This study found higher BMI and waist circumference were independently associated with lower GFR (long term) after living kidney donation bit.ly/CJASN0403

'The future of nephrology depends critically on the recruitment, retention, and training of the next generation...' This Editorial discusses a recent study that suggests most program directors have less protected time than necessary to train fellows bit.ly/CJASN0462

Transplant programs need guidance on essential ApoL1 clinical policy questions. This study found a Delphi consensus panel supported policy options involving discussion and shared decision making among patients, donors, and family stakeholders. bit.ly/CJASN0397

The American Society of Nephrology Journal editors recently created a new ASN Journals’ Editorial Board. This broader editorial board includes editors who work across all three journals to support JASN, CJASN, and American Society of Nephrology360. For more information, visit bit.ly/ASNEdBoard

SGLT2 inhibitors reduce the risk of cardiovascular disease in patients with CKD. This study found SGLT2 inhibitors reduced risk of cardiovascular death, having the most pronounced effects on risk of deaths attributed to heart failure bit.ly/CJASN0470

David C Wheeler

Bone loss after kidney transplantation is highly variable. This study found resolution of high bone turnover, as reflected by decreasing bone turnover markers, associated with BMD gain, while increasing bone turnover markers associated with bone loss. bit.ly/CJASN0368

There have been scarce epidemiological data on the relationship between inflammatory bowel disease and IgA nephropathy. This study shows the potential association of inflammatory bowel disease with higher risk of developing IgA nephropathy bit.ly/CJASN0457

PD is considered equally effective for the treatment of kidney failure as hemodialysis but is less costly. This study found people with intra-abdominal adhesions undergoing PD catheter insertion were at higher risk for abdominal pain or flow restriction bit.ly/CJASN0404

Basic health literacy and trust in physicians can influence medication adherence in patients receiving dialysis. This study found functional and communicative health literacies were positively associated with medication adherence bit.ly/CJASN0392

Chronic interstitial nephritis in agricultural communities (CINAC) is an epidemic of kidney disease affecting tropical & subtropical regions. This Review draws similarities between the kidney injury phenotype of these patients & mice treated with paraquat bit.ly/CJASN0312

Complement pathway activation is a critical driver of inflammation and tissue injury in IgA nephropathy. This study found that treatment with cemdisiran resulted in a reduction of proteinuria at week 32 and was well tolerated bit.ly/CJASN0384

Jonathan Barratt

There has recently been a significant increase in available therapeutics and ongoing clinical trials that directly target the pathogenic mechanisms implicated in immunoglobulin A nephropathy (IgAN). Could complement blockade play a role in IgAN management? bit.ly/4aB5wBo

'As primary payer for most patients with kidney failure, the Centers for Medicare & Medicaid Services is in the best position to encourage the adoption of PD.' This Perspective discusses peritoneal dialysis (PD) expansion and equity in the US bit.ly/CJASN0377

Nephritis is indistinguishable from IgA nephropathy. This study found outcomes in patients with IgA vasculitis nephritis treated with immunosuppression was determined by risk factors & endocapillary hypercellularity & fibrous crescents bit.ly/CJASN0398

Scott Wenderfer

Anemia in patients with CKD is commonly treated with erythropoiesis-stimulating agents (ESAs). However, ESAs increase the risk of major cardiovascular events. This Perspective discusses the use of SGLT2 inhibitors to alleviate anemia in this population bit.ly/CJASN0362

Angiopoietin 2 regulates endothelial function partially mediated by vascular endothelial growth factor-A (VEGF-A). This study found higher angiopoietin 2 levels were linked to cardiorenal risk among those with DKD independent of VEGF-A bit.ly/CJASN0389

Rare or orphan kidney diseases are a complex group of disorders that can be seen frequently in children. This Perspective highlight how children from low- low middle income countries receive inequitable access to disease-modifying therapies bit.ly/CJASN0374

Priya Pais

COVID-19 has posed increased risks of hospitalization and mortality in patients with CKD. This study found a dose-response relationship between the number of BNT162b2 or CoronaVac doses & effectiveness against infection bit.ly/CJASN0376

Esther Chan @ CSMPR HKU Francisco TT Lai

Nephrologists are frequently consulted when the cause of high anion gap metabolic acidosis is not readily apparent. This article discusses the use of a modified version of the CUTE DIMPLES mnemonic in the evaluation of high anion gap metabolic acidosis bit.ly/CJASN0381