Rotavirus vaccines save lives, but some infants may not respond as well due to CMV exposure. A new study uncovers this challenge in HIV-exposed-uninfected babies. 📖 Learn more: bit.ly/3DX1oAq #CelebrateVaccines #Immunology #ChildHealth

How do T-cell integrins influence autoimmune and inflammatory diseases? This new review explores their role and the latest therapeutic advances. Read more in Clinical and Experimental Immunology: bit.ly/3F1Dcd5

Why do some colon cancer cells resist antibody-based treatments? This study explores how miR-132-3p controls CD55 expression and impacts immune sensitivity. 📢 Learn more: bit.ly/43UPEcz

📢 Submit your research to Clinical & Experimental Immunology! 🧬🔬 We publish high-quality studies in translational & clinical immunology, spanning autoimmunity, cancer immunology, infection, inflammation & more. 📖 Learn more & submit: bit.ly/443pf8s

A new MAILD mouse model 🐭, induced by TLR9 agonist and muscle homogenate, closely replicates the pathogenesis of IIM-ILD, including NETs infiltration and TLR9 activation. This model may offer a more accurate alternative to the EAM model. Read now 📖: bit.ly/43AbDFp

🧬 Vaccine response isn’t just about antibodies. This study shows pediatric AIIRD patients generate robust CD4+ T-cell responses post BNT162b2 vaccine—comparable to healthy peers. Read now 🔗 bit.ly/3XSCZ61 #CelebrateVaccines

HYCO-3 hits inflammation from both sides—Nrf2 activation + CO release 🧠🔥 In an EAE model, it dampens microglial and T cell responses, showing promise for autoimmune diseases like MS. 🔗 bit.ly/3Gf7UDk #MS #Neuroimmunology

Oral vaccines protect millions—but why do they falter in low-resource settings? 🌍💉 From microbiomes to maternal antibodies, this review unpacks complex contributors to global disparities. 🔗 bit.ly/42aACy3 #CelebrateVaccines #Immunology

🔬 Explore the link between microglial morphology and function! 🧠 Discover how changes in microglial shape reflect inflammation and tissue damage in the CNS, and why combining histological and genetic approaches is key for deeper insights. 👉 Read more: bit.ly/4ieWE7z

T-cell redirectors like ImmTACs hold huge promise—but potency and selectivity hinge on binding kinetics. This work shows why stronger isn’t always better: optimizing CD3 affinity is key to avoiding a non-signaling “dark state.” Read more 🧬 bit.ly/4luj4Vb

From adaptive designs to machine learning, Phase 3 vaccine trials are embracing innovation to speed up development and improve precision. Learn about the latest advancements in trial design: bit.ly/3RovHDs #CelebrateVaccines 🔬💉

🌍 It's #WorldPIWeek2025, and we're helping to raise awareness of Primary Immunodeficiencies 📖Check out our special collection exploring inborn errors of immunity including Primary Immunodeficiencies 🔗Read it here: immunology.org/publications/j…

🧫 Investigators analyzed potential variations in the number and function of two Treg cell subsets in healthy adults over a two-month period. 📖 Clinical & Experimental Immunology | bit.ly/3EAvf28

A systematic review of 56 cases worldwide reveals patterns of ANCA-associated vasculitis after COVID-19 vaccination. Most patients achieved remission with standard therapy, supporting continued vaccine safety. #CelebrateVaccines 🔗 bit.ly/4jpz9K8

📢 Calling all immunology researchers & clinicians! #FOCIS2025 is the premier event to explore immune-mediated disease pathways & therapies. 📍 Boston, USA 24–27 June 2025 🔗 Details: bit.ly/4iBvkAD #Immunology #FOCIS2025

It’s #WorldMalariaDay 🌍 How does chronic malaria affect your immune system? This study links T cell exhaustion with altered B cell profiles & anaemia in malaria-exposed pregnant women. 🧪 Insightful data for vaccine & immunity research. 🔗bit.ly/3GF9DSD

Pinpointing key regions in the SARS-CoV-2 nucleocapsid protein: a step forward for diagnostics & vaccine development! 💉🔬 #WorldImmunisationWeek #CelebrateVaccines Full study: bit.ly/438kQnu

🔬 This #MSAwarenessWeek, we spotlight new research on neutrophil dysregulation in #MultipleSclerosis. The study shows altered granule proteins & impaired T cell suppression - highlighting a role for innate immunity in MS. Read more: bit.ly/42yJFZI #MSConversations

📉 Why do some immune systems fail to mount a proper response? This study uncovers how mutations in NFKB2 disrupt B-cell function in patients with immunodeficiencies. Full article ➡️ bit.ly/42VTEHz

Why do some children develop MIS-C after COVID-19? Could rare genetic mutations be to blame? A new review connects IFN-I pathway defects to severe SARS-CoV-2 outcomes. 🔗 bit.ly/42Mc5iZ