#OnTheCover [FeFe]-Hydrogenase: Defined Lysate-Free Maturation Reveals a Key Role for Lipoyl-H-Protein in DTMA Ligand Biosynthesis Broderick Lab onlinelibrary.wiley.com/doi/10.1002/an…

[FeFe]-Hydrogenase: Defined Lysate-Free Maturation Reveals a Key Role for Lipoyl-H-Protein in DTMA Ligand Biosynthesis (Broderick) Broderick Lab onlinelibrary.wiley.com/doi/10.1002/an…

A grad student interested in teaching positions? A post-doc looking to diversify? The BU Chemistry PAL program has been a successful way for training toward a PUI position! We are looking for 3 new PALs. You'll have a research and a teaching mentor! academicjobsonline.org/ajo/jobs/21306

Congratulations to Joan on election to the American Academy of Arts & Sciences! American Academy of Arts & Sciences Joan Broderick MSU Chem_Biochem Montana State University

Congratulations to Joan B. Broderick of Montana State University who joins the National Academy of Sciences for her outstanding contributions to biochemistry. #NAS159 Read more: ow.ly/jMFs50IYzho #biochemistry

Dana Longcope of Montana State University has been elected to the National Academy of Sciences for research on the nature of solar magnetism, and magnetic topology. #NAS159 Read more: ow.ly/n3sV50IYEuX #physics

Congrats to Katherine on graduating today with a B.S. in Chemistry/Biochemistry. She has been an awesome research student and lab mate and we will miss her!

We are working hard at the Metallocofactors GRC! #Metalloco22

.Joan Broderick & gang review [FeFe]-hydrogenase in vitro maturation. Out now with Angewandte Chemie! doi.org/10.1002/anie.2…

We have a fantastic department with so many amazing young faculty - come work in this stimulating and collegial community! Bozeman is not bad either!

Happy to share our most recent review on radical SAM enzymes: FEBS Press febs.onlinelibrary.wiley.com/doi/10.1002/18…

A new mini review from our lab focusing on in vitro [FeFe]-hydrogenase maturation. Interesting chemistry & biochemistry with still so much to learn!

Computational Description of Alkylated Iron–Sulfur Organometallic Clusters | Journal of the American Chemical Society Montana State University MSU Chem_Biochem NorthwesternResearch Northwestern Northwestern Chemistry #Computational #Alkylated #IronSulfur #Organometallic #Clusters pubs.acs.org/doi/10.1021/ja…

New in ChemComm: Joan Broderick and colleagues report the semisynthetic maturation of [FeFe]-hydrogenase, revealing new insights into the nature of H-cluster biosynthesis. Broderick Lab bit.ly/46W7lHy

ENDOR Spectroscopy Reveals 5′-Deoxyadenosyl Radical in a Radical SAM Enzyme Active Site is Chaperoned by Interaction with Methionine-Bound [4Fe–4S]2+ Cluster JACS Montana State University Northwestern Chemistry NU Wildcats Football #ENDOR #Adenosyl #Radical #Methionine #Chaperone pubs.acs.org/doi/10.1021/ja…

We showed that upon reductive SAM cleavage, the 5’-dAdo radical moves *towards* the [4Fe4S] cluster, on its way to forming the omega organometallic intermediate. The once elusive radical, triangulated! Broderick Lab @MartinMosqueraT

Kudos to grad student Will Walls Broderick Lab on outstanding work that led to his first J. Am. Chem. Soc. paper! Congrats also to undergrad Tyler Delridge, Will Broderick, and collaborators @AnnaVagstad and Piel Lab. Radical epimerization in RiPP maturation.

Congrats to @AnnaVagstad bringing this amazing story to the finish line! Thank you to everyone involved from Broderick Lab for the fantastic collaboration! If you are interested in the enzymatic mechanism of peptide epimerization by rSAM, make sure to read it.👇

Check out our #potw! Thanks Alina for presenting this cool work about a radical SAM epimerase by the Broderick lab. Read to learn how a conserved Cys to Ser mutation helped trap and characterize the α-C • intermediate of OspA using rapid quench & EPR pubs.acs.org/doi/10.1021/ja…

Fantastic research group camping outing last weekend: two nights of a northern lights show, a beautiful float and card games. Perfect weather only a few days after an 8” snow storm. Broderick Lab