New year, new paper! Now published in nature. We identified and characterised diverse immune cell states in plants under pathogen attack. My postdoc work in Joe Ecker lab at Salk Institute. nature.com/articles/s4158…

Our tour de force into the nucleolar world — a stunning exploration of spatial organization and the functional choreography of ribosome biogenesis now out in Nature✨ tinyurl.com/5n7jk3uz Led by Sofi Quinodoz, Lifei jiang, brangwynnelab, with theory partners Qiwei Yu,

Resurrection plants: The drought-resistant 'zombie plants' that come back from the dead (BBC) bbc.com/future/article…

Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function: Molecular Cell cell.com/molecular-cell…

#TansleyReview: Exploring the untapped potential of #single-cell and spatial omics in plant biology By Tatsuya Nobori 👇 📖 nph.onlinelibrary.wiley.com/doi/10.1111/np… #LatestIssue Wiley Plant Science

A major technological advancement that opens up an entirely new area of cell biology ... @nature reports a versatile platform for high-throughput functional interrogation of RNA localization in living cells and organisms. doi.org/10.1038/s41586…

Will AI-designed proteins break biologics patents? If your IP strategy still relies on “≥80 % sequence identity,” it might be time for a rethink. Thread👇 Tools like ProteinMPNN from the Baker Lab, take an existing e.g. AbAg complex or enzyme and can replace substantial parts

Spearhead Bio, a Danforth Technology Company startup, has received a grant from U.S. National Science Foundation that will allow them to fast-track their breakthrough genome engineering technology to develop corn varieties equipped for ag’s biggest challenges. Read more: loom.ly/zHfitlo

How do cells clean up misfolded proteins when they divide? This study finds that the cleanup crew includes the ER chaperone BiP and the proteasome, and kicks in right as cells finish dividing. Surprisingly, one major cell cycle regulator isn’t involved. elifesciences.org/articles/96675…

Design of intrinsically disordered region binding proteins | Science science.org/doi/10.1126/sc…

Reconciling competing models on the roles of condensates and soluble complexes in transcription factor function dlvr.it/TLzqpf

Undruggable ‘disordered’ proteins become druggable with new AI techniques from David Baker. Science Magazine science.org/doi/10.1126/sc…

Biomolecular condensates as regulators of enzymatic reactions: nature.com/articles/s4428…

In a new Science study, researchers report a powerful tool to design small, folded protein domains that interact tightly with intrinsically disordered protein regions. The authors suggest potential applications in cellular imaging, in vitro peptide capture, and modulating cell

Potato evolved from tomato 9 million years ago. cell.com/cell/fulltext/… Natural History Museum Sandra Knapp University of British Columbia Loren H. Rieseberg Sichuan University Jianquan Liu #CAAS Sanwen Huang @cellcellpress

To all of the folk saying we need deep learning for RNA-seq prediction...

A subset of group S1 bZIP transcription factors controls resource management during starvation and recovery in Arabidopsis (Theresa Wildenhain , Cezary Smaczniak , et al) doi.org/10.1093/plcell… #PlantSci ASPB

Structural mechanism of H3K27 demethylation and crosstalk with heterochromatin markers dlvr.it/TMMd6j

Ever wondered what else SETD2 does beyond transcription? 🧬 Check out our new Nature Cell Biology study. Awesome work from Abid Khan (Abid Khan) showing how SETD2 moonlights to safeguard the genome during cell division. nature.com/articles/s4155…

Leading a lab, and all it entails | Science science.org/doi/10.1126/sc…