When transplanted into injured adult rat brains, human brain organoids can grow, send out neural signals, and respond to visual stimuli. Penn Medicine Read more in Cell Stem Cell cell.com/cell-stem-cell…

The latest advance in brain organoids. Human neural implants are surprisingly good at integrating with host brains in adult rats. Penn research could pave the way to treating brain injuries with organoid grafts ft.com/content/d8672e…

Human brain ‘organoids’ grafted into rats take note of light and pattern go.nature.com/3HZFg7T

Congratulations to our undergraduate researcher, Nitin Seshadri '25 for receiving the UPenn CURF Research Grant to conduct research on the “Effect of Traumatic Brain Injury on Visual Stimulus Reaction Time".

This month’s lab dinner was all about celebrating Dennis Jgamadze’s new position as Research Assistant Professor of Neurosurgery. Congrats Dennis, so well deserved!! Penn Neurosurgery

Thank you so much to Cell Stem Cell for highlighting our paper and including it in their stand-out stem cell research list!! Check the paper out here: cell.com/cell-stem-cell… Penn Neurosurgery

For Current Biology, Isaac Chen, MD contributed to a paper where it was learned that odor representations from nostrils are segregated in the piriform cortex, showing an olfactory coding scheme that parses info across nostrils in a single inhalation. ➡️ spr.ly/6014uqMBn

For a new publication in Nature Communications, Steven Brem, Sasha Ulyanova, WolfLab, and BrainRepairLab (Dr. Isaac Chen Lab) contributed to a study titled, "CHEX-seq detects single-cell genomic single-stranded DNA with catalytical potential." ➡️ spr.ly/6011uItOH

Our latest paper highlights the most recent progress and remaining challenges in using cell replacement therapy for the treatment of Parkinson’s Disease and Cortical Injury Check it out here: mdpi.com/2076-3425/13/1… Penn Neurosurgery Penn Medicine @DennisJgamadze

A big congratulations to our lab member and medical student researcher, Shikha Singh, for an acceptance into the Master of Science in Translational Research (MSTR) program at the University of Pennsylvania. Keep a look out for her great work!

First lab dinner of 2025! Happy New Year from the Chen Lab!

Now out in nature, Yusha Sun, Xin Wang, and additional members of the Song and Ming Labs, BrainRepairLab (Dr. Isaac Chen Lab), and DrORourke labs introduced trans-synaptic tracing tools from circuit neuroscience to study the whole-brain connectome of glioblastoma. ➡️ spr.ly/6011a7Fqc