Why sometimes you have to overpay $XBI

Antibody drug conjugates (ADCs) are all the rage, for good reason.

They're generating stellar efficacy results in clinic, though they're not perfect.

I looked through 40+ ADC companies founded after 2010 to see what each was trying to improve on and with what new approach. ⬇️

📝This is significant - pls take a moment to note and familiarize if involved in oncology therapeutics

Heaven - a place where biotech M&A happens all day everyday! $XBI

Sorry had to do it - its Friday! E. Eric Tokat 🤣♥️🐐

🎥🩸Blood Clot Removal in Action

Epoch 15: Sweat Equity - Your Weekly Biotech News Fix

👉 Neuropsychiatry is back!
👉 $NVS gets active in deal making
👉 $IPSC joins the autoimmune party
👉 Private biotech funding rises
👉 $VRTX buys $ALPN for $4.9B
👉 Vaccines make a statement at #AACR24
👉 $DOJ comes after…

For anyone interested
I made a tutorial covering how to make the nanopore sequencing animation I posted last week😊
youtu.be/VV8b8A8_feM

#b3d #MolecularNodes #sciart

Cell, Nature, Science, PNAS

The internet is hilarious for those that have managed to keep their sense of humor 🤣

Exited to share our new paper by Gang Du @ , Liam Liam Healy, Liron David Liron David and others on GSDMD palmitoylation. “ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D” in Nature nature.com/articles/s4158…. Even full-length GSDMD can form pores!

big if true

Check inbox at noon for this weeks SweatEquity newsletter which will highlight what caught our attn this week in biotech....

Designed to be consumed as a quick scroll with links those interested in deep dives

(L!nk to substa**ck in b!o)

Categorizing Immunotherapy

Tumour-Infiltrating Lymphocytes (TIL)
T Cell Receptor-Engineered T cells (TCR-T)
Chimeric Antigen Receptor T cells (CAR-T)
Chimeric Antigen Receptor Natural Killer cells (CAR-NK)
Chimeric Antigen Receptor Macrophages (CAR-M).
Chimeric Antigen Receptor…

RNA Engineering: enhancing expression & stability

Self Amplifying RNA
saRNA is a type of synthetic RNA engineered to contain not only the coding sequence for a specific protein but also elements derived from RNA viruses that enable self-replication within host cells. This unique…

CD47 in liquid tumor $ALXO

Can't believe we are back to the RIF headlines....the BIG difference these are now largely coming from pharma which was absorbing much of the biotech RIF in 2023.

Everything is fine.

And more Pharma RIF: Boehringer Ingelheim to lay off staff amid biosimilar challenges