🔥The 9th Round of Easy Loan, Earn $40 Reward is in progress❗️ ⏰ Promotion Period: January 15th - Feburary 15th, 2025 👉 Register now and check more details at gate.io/campaigns/358

A #PDRA position in #evolutionary #microbiology is available in the lab of Dr James Hall (UoL) as part of a BBSRC project in collaboration with the MultiDefence Consortium (sites.exeter.ac.uk/multidefence/) Information/Apply tinyurl.com/3p85rrtw Faculty of Health and Life Sciences Inst of Infection Veterinary & Ecological Sciences Research at University of Liverpool

My favourite discovery ever has just come online. Can I please tell you about some seriously wacky molecular biology? The story starts with a reverse transcriptase that SOMEHOW defends bacteria from viruses. (👇 I recommend sound ON for the video 🎹) 1/

Congratulations to Tim Blower and Tom Happy to be involved in this wonderful collaboration! NTase toxins are truly amazing! Dissecting the antitoxin-mediated Toxin auto-phosphorylation rdcu.be/dSXxi

Researchers @blowerlab and colleagues use biochemistry, biophysics, and crystallography to characterize a mechanism of antitoxin induced autophosphorylation that can neutralize nucleotidyltransferase toxins of Mycobacterium tuberculosis nature.com/articles/s4146…

journals.asm.org/doi/10.1128/jv… Our thoughts on how toxins bound to TAs are activated: via conformation changes, not by selective degradation of ATs by a protease (makes little sense since both are structured). Remarkable insights determined by studying various TAs as they inhibit phage.

When experiments don’t work... build a phage costume! 🎃 Happy PHAGEOWEEN!!! 👻🧬#Teamwork

Thrilled to share my latest postdoc paper published in Nature Communications NTase toxin targeting serine tRNA 3'-ends by CMP addition in M. tuberculosis H37Rv. Thanks to all the co-authors, Pierre Genevaux Tim Blower Olivier Neyrolles rdcu.be/dZle4

Using cryoEM we understood the structural basis of chiral DNA wrap by bacterial gyrase (and also produced the most complete/highest resolution E coli gyrase model to date). John Innes Centre DurhamUniversity Malopolska Centre of Biotechnology UJ

Over the moon to share some amazing news—I’ve been awarded an MRC Career Development Award to pursue my research at the University of Glasgow UofG Sii ! 🎉 Can’t wait to get started on this exciting new chapter. Stay tuned—I’ll soon be advertising a PDRA position!

The final version of our Serratia paper is now out! Congrats to Tom Cummins and (X-less) Suraj, and a big thank you to Tim Blower and Stephen Garrett. tinyurl.com/3vnyvufa

Super opportunity to join Giusy in Glasgow!

For those of you who approached me at Microbiology Society #Microbio25 (and anyone else interested!!), this is your last chance to apply for our PDRA position. Come join us in Glasgow!

We are delighted to host Professor Tim Blower Tim Blower as keynote speaker to our MID symposium Life Sciences Date: 20th of June Venue: GLT1 We invite MBio, PhD students and Postdocs to submit abstracts for posters and talks by 11th of June to Rodrigues Lab