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Venous thromboembolism (VTE) affects 1 million Americans yearly. A recent study in Blood Advances shows 1 in 3 medical patients had misclassified #VTE risk, leading to inappropriate treatment for half. Read the study: ow.ly/h6ll50W0tg6 Blood Journal

An elevated body mass index is a significant contributor to overall cardiovascular diseases and may contribute to one-quarter of the population’s attributable risk for venous thromboembolism. ow.ly/RTBF50W0wlR #healthservicesandoutcomes #thrombosisandhemostasis

In this study, the first phase 2 trial in which prophylactic tocilizumab was administered to patients who had received umbilical cord blood, as opposed to bone marrow or peripheral blood, as a stem cell source. ow.ly/7gu750W0wpr #InsideBloodAdvances #transplantation

Myeloma and its precursor, monoclonal gammopathy, are more common in individuals with Black ancestry and are associated with immune dysfunction. ow.ly/x4X750W0wxv #immunobiologyandimmunotherapy #plasmacelldisorders

This study comprises 211 adult patients diagnosed with MPN-AP/BP in 2017 or later from 9 academic centers. ow.ly/zj1950W0wzr #myeloidneoplasia

Allogeneic hematopoietic cell transplantation remains a potential curative option for patients with relapse/refractory Hodgkin lymphoma. ow.ly/7qrM50VTy7x #lymphoidneoplasia #transplantation

American Society of Hematology/International Society on Thrombosis and Haemostasis 2024 updated guidelines for treatment of venous thromboembolism in pediatric patients ow.ly/9VOU50W0wGJ #clinicalguidelines #thrombosisandhemostasis

Pola-M-CHP did not demonstrate a clinical benefit over Pola-R-CHP in this small study and additional dose optimization may be required. ow.ly/EcSk50W0wLv #clinicaltrialsandobservations #lymphoidneoplasia

KRAS, NRAS, BRAF, or MAP2K1 mutations are more prevalent in secondary MH, whereas PTPN11 mutations are exclusive to primary MH. ow.ly/XeFR50W0wZn #clinicaltrialsandobservations #myeloidneoplasia

In non–low-risk AML, the addition of VEN to FLAI induction chemotherapy gives high rate of CR and limited toxicities. ow.ly/CSJZ50W0x2K #clinicaltrialsandobservations #myeloidneoplasia

Clinical benefits of PTCy dose reduction may include faster engraftment and T-cell recovery and less severe BK virus cystitis/urethritis and mucositis. ow.ly/jc3I50W0xa0 #clinicaltrialsandobservations

SerpinPC treatment of factor VIII–deficient mice fully restored hemostasis in a tail clip model in a dose- and time-dependent manner. ow.ly/G4E450W0xcR #thrombosisandhemostasis

The use of GLP1-RA is associated with a lower risk of 1-year VTE compared with DPP4i in patients with T2DM. ow.ly/tfOw50W0xf7 #thrombosisandhemostasis

PRMT5 inhibition reduces clinical signs of HLH, including physical traits, cellular populations, and inflammatory cytokines in this model. ow.ly/orWJ50W0xfG #immunobiologyandimmunotherapy #phagocytesgranulocytesandmyelopoiesis

Ex vivo reprogramming of CLL T-cell mitochondrial activity enhances CAR T-cell efficacy and persistence in an immunocompetent murine model. ow.ly/xtKT50W0xj0 #immunobiologyandimmunotherapy #lymphoidneoplasia

Incorporating rituximab into the INCTR chemotherapy protocol for treating EBV-positive BL in Sub-Saharan Africa is both feasible and safe. ow.ly/5FhW50W0xkK #lymphoidneoplasia

This post hoc subgroup analysis of older patients enrolled in POLARIX showed consistency with the overall POLARIX population results. ow.ly/iXqc50W0xm5 #clinicaltrialsandobservations #lymphoidneoplasia

CAR-T cell rescue after second line appears to overcome the poor prognosis of HGBL compared with other LBCL all characterized with FISH. ow.ly/9j7r50W0xmE #lymphoidneoplasia #healthservicesandoutcomes

The surface protein CD33 is amenable to multiple modes of editing without impact on hematopoietic cell reconstitution. ow.ly/5NgG50W0xoL #genetherapy #hematopoiesisandstemcells

BCR-ABL drugs differentially modulate parasite and thrombin-induced activation of human brain endothelial cells. ow.ly/C2KQ50W0xbH #vascularbiology