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Happy 10th birthday Open Targets! 🎉 Thank you to everyone who has worked to make Open Targets what it is today. Here's to the next 10! 🥂 #OpenTargetsAt10

Happy birthday Open Targets ! These 10 years have gone so fast! Here's to many more years of doing awesome science together! 🥂🍾🎉 #OpenTargetsAt10

I am thrilled and honored to have been a part of Open Targets for the last 8 years (almost from the inception☺️)! I enjoyed a lot hearing about all the ongoing projects over the last 3 days! Cheers to another ten years🥂!

✨✨ Proud of Matilde Conte Matilde Conte who is representing our lab at #ESID2024! Do not miss her poster today at 12:50 on "Tracing variants from intermediate traits to severe monogenic conditions" ✨✨

@Andi_Microscopy and I structurally characterized beta cell cilia by #vEM and #UExM. It's out today in Nature Communications! We describe axoneme ultrastructural organization, as well as some novel physical contact between beta cell cilia and neurons. Link below! nature.com/articles/s4146…

🐣 So happy! With francesco nicassio and many others we’ve put together a network of >20 labs in Milan working on various flavors of RNA biology. Looking forward to a year of stellar talks by students and postdocs, new ideas, collaborations and much more The RNA Society Lexogen

Great to be at #ASHG2024 , my group are presenting three posters: Diffusion autoencoding models + GWAS of cardiac MRI in 70k subjects, IPH detection in 2,500 plaques using MIL+MACE prediction and our work looking at crypt morphology variation (H&E+spatial) in healthy + IBD GI.

Come say hello to Francesco Cisternino, Sara Ometto and Emanuel Soda!

Impressive work by Sara Ometto Soumick Craig Glastonbury and the whole team🎉🥂! Well done everyone! Check it out!

Excited to present me and Soumick work at #ASHG ! Tomorrow from 14:30, board 4141W: Unsupervised phenotyping and genetic discovery in 62k cardiac MRIs using diffusion autoencoders See you there 🤗

Curious about how unsupervised learning can reveal phenotypic and genetic insights from MRI images? Don’t miss the chance to check out Sara Ometto ‘s incredible poster, showcasing pioneering work done alongside Soumick in the Craig Glastonbury group! glastonburygroup.github.io/CardiacDiffAE_….

🔬Our Carlotta Barelli and Nereo Kalebic group with our @IorioLab identified ADD3 as a key gene driving glioblastoma stem cell shape and tumour connectivity, uncovering growth and therapy resistance 📰Published in Life Science Alliance with support from Fondazione AIRC per la ricerca sul cancro humantechnopole.it/en/news/cancer…

Huge congratulations to Nereo and Carlotta for this fantastic paper!🎉🎉🎉 Check it out!

Congratulations to Chiara Ossola for a successful PhD defense - the first in the lab 👏👏👏. Check out our latest preprint for more on Chiara's PhD work: biorxiv.org/content/10.110…

A chapter of my PhD thesis is out as preprint. Check out our new findings on roles of Prp16 in pre-mRNA splicing 🧬 in Cryptococcus neoformans.

Modern GWAS can identify 1000s of hits but it can be hard to turn this into biological insight. What key cellular functions link genetic variation to disease? I'm excited to present our new work combining associations + Perturb-seq to build interpretable causal graphs! A🧵

Less than a month to apply! If you're a PhD student in human genetics, don't miss this unique opportunity. We have a stellar lineup of tutors promising immersive scientific and mentoring discussions.

Postdoc opportunity to join Mary-Ellen Lynall and my group on this exciting project to look into the genetic drivers of immune system deregulation in schizophrenia.

Great collaboration as detailed in the thread and another first author paper for Francesco Cisternino from my group! 😊

A new preprint from our group: biorxiv.org/content/10.110…