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CALL FOR SUBMISSIONS NOW OPEN! Submit to Biology of Sex Differences Biology of Sex Differences collection "Sex/Gender Differences in Social Determinants of Health at Specialized Centers of Research Excellence (SCORE) on Sex Differences"🔬 Due Nov 2024. Details here: biomedcentral.com/collections/SG…

New article: Authors studied the role of microRNA-21 (miR-21) in altered energy homeostasis and BAT thermogenesis in a #PCOS mouse model of peripubertal androgen exposure. Read their results: ow.ly/NxJj50SzMz5

New article: While previous studies explored #SexDifferences in membrane excitability and synaptic glutamate transmission "to our knowledge, none have specified NAcSh D1R + MSNs from mice during pre- and mid-adolescence," authors write. Read the research: ow.ly/M4cJ50SBq52

New article: this study "aimed to investigate the combined effects of high-fat diet (HFD) induced obesity and repeated stress on fear-related behaviors, metabolic, immune, and hypothalamic outcomes in male and female mice." ow.ly/UMux50SCiFf

New article: "This review focusses on the biology of sex differences in CF, asthma and COVID-19, and the cellular mechanisms by which estrogen can have either detrimental or beneficial effects in these diseases," authors write. Read more: ow.ly/KZc250SGgg5

Biology of Sex Differences is excited to invite SCOR(E) Directors to submit articles from their Specialized Centers of Research (Excellence) addressing #gender #SexDifferences in social determinants of health as it pertains to health topics of focus: biomedcentral.com/collections/SG…

New article: "This study investigated the effects of biological sex, housing condition, and time-of-day, on social motivation using the social operant model," authors write. Read the results:ow.ly/c3Fg50SHf3U

New article: "This study explores sexual differentiation of the forebrain using single nucleus RNA-sequencing in the anemonefish Amphiprion ocellaris, producing the first cellular atlas of a sex-changing brain," authors write. ow.ly/bGYO50SJ4yR

New article: "We lack a consensus transcriptomic profile that considers sex and differentiates specific cerebral regions," authors note. Read their study of #schizophrenia and #SexDifferences: ow.ly/a3kg50SM90S

New article: Authors investigated the expression pattern of the Smad4 and FoxH1, which may play important roles in ovarian development in M. albus. Read the results: ow.ly/IFWn50SO5ho

New article: Authors "sought to delineate how the IUP effects HPA and HPG brain receptors, peptides, and enzymes (hereafter components) in utero and how these influences may differ between males and females." Read more: ow.ly/J1b150SRZkz

New article: Authors found "genes associated with key biological pathways including cell proliferation, immune response and drug metabolism are differentially regulated between males and females in both healthy lung tissue and tumor." ow.ly/BINJ50SSQcO

#FlashbackFriday Authors in 2012 studied #SexDifferences in high density lipoprotein (HDL) apolipoprotein C-III (apoC-III) in American Indian youth to understand possible risk for type 2 diabetes. Check out the results: ow.ly/1KbV50Q13wi

New article: Authors found that "sex dimorphic differential methylation with associated differential gene expression in the first trimester placenta is small" but significant genes remain in play. Read more: bsd.biomedcentral.com/articles/10.11…

New article: In this study, authors conducted a comprehensive examination of molecular distinctions and regulatory networks across 27 cancer types, delving into sex-biased effects. Read the results: ow.ly/nFm850T4Zle

New article: Authors examined sex- and stress-specific impacts on left ventricular hypertrophy (VH) after aging & hypothesized that early-life chronic stress exposure impacts behavioral and physiologic responses that predict cardiac remodeling: ow.ly/LcbY50T9VSj

New article: Authors created MetaFun as an easy-to-use web-based tool to meta-analyze multiple transcriptomic datasets with a sex-based perspective to gain major statistical power and biological soundness. Check out the tool: bsd.biomedcentral.com/articles/10.11…

New article: The study "Whole-genome de novo sequencing reveals genomic variants associated with differences of sex development in SRY negative pigs" provides a theoretical basis for understanding the molecular background of XX DSD pigs, authors write. ow.ly/WbNs50Tei5v

New article: Authors aimed "to analyse potential sex disparities regarding the tolerability and effectiveness of lipid-lowering therapy in patients with and without reported statin intolerance who are being treated at a lipid-outpatient clinic." ow.ly/kcIS50TeijC

New article: Authors here aimed to "investigate the difference of reactome pre-Notch expression and processing between males and females by using gene to function analysis in FUMA." Read their results: bsd.biomedcentral.com/articles/10.11…