Our pre-print into recurrent sars-cov-2 mutations in immunodeficient patients is out on medrxiv, please give it a read! Nick Loman Tom Peacock @myxosparkus Professor Alex Richter Josh Quick Nicola Cumley Sam Nicholls @samstudio8.bsky.social

Spike mutations seen in this study were not among the most common found by Tom Peacock & Nick Loman in their recent study of chronic infections, indicating Sotrovimab treatment creates evolutionary pressure resulting in uncommon antibody-evading mutations. 3/7

Signing off on the integrity of the CLIMB-BIG-DATA CLIMB-COVID COVID-19 Genomics UK (COG-UK) Consortium daily data ingest for the last time today... Having spent nearly two years looking after these pipelines it's going to be incredibly weird to not be thinking about them over the coming weeks.

Me "fixing" a broken climb-covid pipeline be like Sorry European Nucleotide Archive (ENA) Sam Nicholls @samstudio8.bsky.social

Nothing makes me feel more like a midlands bumpkin than using the tube for the first time in a decade for #NanoporeConf

Angry foodie noises. What on earth is the point of a wagyu burger???? Just like add fattier mince to the mix of cheaper beef ffs

Omg so proud of you buddy 😁

What shall we do with all the Sars-CoV-2 sequencing infrastructure & expertise? Apply it to even *more* pathogens, of course! In this case, adenovirus F41, cause of childhood gastroenteritis & linked to unusual paediatric hepatitis cases osf.io/6jku5/

Waffle Discussions with Dr Emma Hodcroft Áine O'Toole Sam Wilkinson 🙃 #GrandChallenges

Had a really fun time at #GrandChallenges2022 in Brussels running a genomics outbreak tabletop on behalf of ARTIC Network with arambaut Ian Goodfellow, huge thanks to Áine O'Toole Dr Emma Hodcroft Sam Wilkinson for putting together some fantastic materials. We hope to share them online soon!

Thanks to everyone for coming to the Microbes & Food Safety Bioinformatics Hackathon. The main takeaway is that ChatGPT is coming fast and will fundamentally change how bioinformatics is performed

We are very excited to have the very first P2 right here in Birmingham. Thanks to all at Oxford Nanopore for making it happen!

Also a reminder about our *NEW* MRes in Microbial Genomics - please share with your undergrads. It aims to train genomics literate microbiologists, applications are open and I'm happy to be contacted directly to discuss. birmingham.ac.uk/postgraduate/c…

Omg Aaron Pomerantz, PhD did I just see you get thanked todays true facts video? Screw nature papers, that's how you know you've made it 😁 youtu.be/tEv23nApEog

ARTIC #mpox resources! Guides to setup #sequencing #bioinformatics and #analysis artic.network/mpxv/resources Wellcome Oxford Nanopore Illumina #molecularepidemiology #pathogen #pathogensurviellance #bioinformatics #epidemiology #virus #outbreak #clinicalvirology