The #PACEtomo paper is now published rdcu.be/c0OxR📜🥳 Since the preprint, Fabian made quite a few improvements and added new scripts for tilt axis offset and sample geometry measurement.🔬🧑‍💻 Thanks to the reviewers for their helpful suggestions!🤓🛠️🙂👍

Dear #cryoEM commuity, the FRISBI |Instruct-ERIC structural cryo-EM facility hosted at IGBMC (Strasbourg.eu,France) is recruiting a research engineer for enforcing our team! The selected candidate will join us for running the uscopes & develop cool methods! plz PM me for more info

Time for another #GW4cryoEM seminar. Nils Marechal from the IGBMC BioS-ME will talk remotely via zoom to Bristol Biochemistry to give an overview on the EM facility in Strasbourg with a particular focus on affinity grids. Don't miss this opportunity!

Congrats to Patrick Schultz's team for their article on the structure of the NuA4/Tip60 complex. They reveal its structure, how and why it acts at a distance from its binding site. Great collab with Dom Helmlinger CRBM 📕 Nature SMB 📰 tinyurl.com/35uft9ye

🎉 Kudos to Vignesh Kasinath and Cech team for revealing a stunning structure & applying streptavidin grids innovatively! Shedding light on the fascinating functional role of G4 RNA, pushing the boundaries of our understanding. Fantastic achievement! science.org/doi/10.1126/sc…

Bored to look at schematic representation of #streptavidin affinity grids ? Here is a real image of the 2D crystal folding on itself. One can see within an unique micrograph both frond and side views of the affinity grid capturing its prey through biotinylated DNA !

Excited to share a pre-print by Vita Vidmar and Céline Borde in collaboration with olivier espeli and Valerie Lamour about the interplay of #Transcription and DNA topology: biorxiv.org/content/10.110…

We are excited to share our latest work on the cooperation between RNA polymerase and the ribosome in bacteria: science.org/doi/10.1126/sc… The work was supported by IGBMC, Inserm, CNRS 🌍, -, @ERC_research, IMCBio Graduate School, and Instruct-ERIC. 1/7

We are pleased to highlight this article published by Gruber Lab at Dubochet Center for Imaging (DCI). Florian Roisné-Hamelin and collaborators used electron microscopy — and in particular our streptavidin affinity grids — to reveal the mechanism by which Wadjet binds to the plasmid to initiate loop extrusion.

New preprint: Using #CryoEM, our #Streptavidin grids IGBMC, and MD-simulations,@FabioLapentaand co-workers solved near atomic structure of the human Major Vault Protein and analysed its dynamics ! biorxiv.org/content/10.110…

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