How do patients with #MS acquire disability? Do DMTs delay clinical progression? Have a look at this paper on Brain bit.ly/3rs4OC5 @MyelinIcm

Here we go, the first demonstration in-vivo that lesion remyelination protects surrounding tissues from microstructural damage in #MultipleSclerosis! @MyelinIcm Vito A.G. Ricigliano Andrea Lazzarotto

The role of glial cells in multiple sclerosis disease progression | Nature Reviews Neurology nature.com/articles/s4158…

Brilliant: Myelin as energy reservoir in the central nervous system

Did you ever wonder what all the oligodendrocyte precursors in the brain are up to when they don’t make myelin? They fine-tune circuits! Funded by European Research Council (ERC) & @DFG_public. Congratulations Yan & all involved. Great collaboration with @portugueslab. nature.com/articles/s4159…

Editors of #eanpages Benedetta Bodini and M. Rakusa speak with J. Sellner, asking three key questions on one hot topic in neurology. Today's topic is #Longitudinal analysis reveals high prevalence of #EpsteinBarr virus associated with #MultipleSclerosis vimeo.com/674436187

Have a look at our novel method to generate individual maps of cortical remyelination in people with MS! Félicitations Andrea Lazzarotto! MSJ @MyelinIcm European Academy of Neurology Vito A.G. Ricigliano #MultipleSclerosis

Identification of early neurodegenerative pathways in progressive multiple sclerosis nature.com/articles/s4159…

Inspiring conversation with Kailash Bhatia, at #EAN2022 European Academy of Neurology - deep clinical phenotyping allows cutting-edge research to translate to personalised medicine for the treatment of #movementdisorders

#MSJournal: researchers including from Paris Brain Institute & Padova Neuroscience Center use a multimodal & multicompartment approach to explore single-patient cortical and WM lesion demyelination & remyelination, and generate clinically relevant indices of #myelin repair ➡️ bit.ly/3nqMTZJ

When remyelination fails in periventricular lesions in people with #multiplesclerosis, atrophy develops in connected cortical regions! Check our last paper published in ⁦Brain⁩ - ⁦Institut du Cerveau - Paris Brain Institute⁩, with ⁦⁦@MyelinIcm⁩ academic.oup.com/brain/advance-…

Lublin et al. analyse the largest clinical trial dataset in MS - with ∼35 000 patients - to address questions including the relative contribution of relapses to disability worsening, and the extent to which treatments delay disability accumulation. bit.ly/3qRGysi

So honored and excited to join the Scientific Committee ⁦⁦AISM - Associazione Italiana Sclerosi Multipla⁩! Great science, great people! With ⁦Paola Zaratin⁩ Matilde Inglese ⁦Stefano Previtali⁩ ⁦Pluchino lab - Regenerative Neuroimmunology⁩ ⁦Dr Antonio Scalfari⁩

Two days of great scientific discussions at the advanced course of #MRI in #multiplesclerosis in Milan! Thank you Mara Rocca and all the great team @Neuroimaging_Research_Unit_SanRaffaele! With Paolo Preziosa Jaume Sastre-Garriga Georgina Arrambide @ThINk_Basel Menno Schoonheim and many other colleagues and friends 😊

After 3 years working Paris Brain Institute in the @MyelinIcm team, It was a great pleasure to defend my PhD! A big thank you to the jury for the great discussion. A spécial thanks to Benedetta Bodini and Stankoff Bruno for their inspiring mentoring along these years.

Did you know that 60% of lesions in #MS have a smouldering component that is critical for neurodegeneration? Check our last paper - just published in the Annals of Neurology ANA Journals! With @MyelinIcm Maryem Hamzaoui Stankoff Bruno Andrea Lazzarotto Paris Brain Institute

Lazzarotto et al. used advanced MRI to study cortical myelin loss and repair in 140 people with MS followed for 5 yrs, and conclude that early-stage myelin repair is effective at preventing long-term accumulation of irreversible clinical disability. tinyurl.com/47whkvrm

Two fruitful and enjoyable days of sharing scientific projects and exploring avenues for collaboration between the Barcelona and Paris groups! Stankoff Bruno Benedetta Bodini Céline Louapre, Elisabeth Mallory, NAIT-OUMESMAR Brahim Hôpital Pitié-Salpêtrière AP-HP Cemcat Vall d'Hebron Vall d'Hebron Institut de Recerca