Our postdoc Chunlei Jiao presented his recent findings at #CRISPR2023 today. If you have the chance also look at posters number 41, 43, and 48 from other lab members Katharina Wandera Anzhela Migur Oleh Dmytrenko 🇺🇦

Great way to round out @crispr2023 #crispr with the conference dinner at the Wurzburg Residence!

Did you enjoy @crispr2023 or want to come to the next one! The #crispr conference will be in ⁦ChristchurchNZ⁩ organised by ⁦Peter Fineran⁩, ⁦Dipa Sashital⁩ ⁦Gavin Knott⁩ and ⁦Bridget Watson⁩. Check out the website crispr2025.org

#CRISPR arrays are a compact way for nature to encode #gRNAs, but their ability to acquire new spacers keeps them longer than necessary for CRISPR technologies. #HIRI's Beisel Lab now shows that CRISPR-Cas9 arrays can be shortened without compromising: doi.org/10.1080/154762…

Listen up, #CRISPR Fan(zor)atics! ✂️🧬 In a new Molecular Cell spotlight, Beisel Lab's @copa_bio recaps Feng Zhang's recent remarkable discovery describing eukaryotic #RNA-guided DNA endonucleases, called Fanzors. Read more here: authors.elsevier.com/a/1hjJC_OylrlC…

A cell-free transcription-translation pipeline for recreating methylation patterns boosts DNA transformation in bacteria biorxiv.org/cgi/content/sh… #bioRxiv

Having trouble with transforming your favorite bacteria with valuable genetic cargo? Try IMPRINT🙌🏻! A sophisticated TXTL-based pipeline developed by Justin Vento Beisel Lab Fun and long-lasting collaboration between Nathan Crook Beisel Lab members! Grateful to be part of it☺️

Such as pleasure to host Beisel Lab as a #ChafferFellow University of Otago Microbiology and Immunology Otago. An amazing tour de force talk today titled “#CRISPR: a bottomless well of discovery and innovation”

(1/2) 🚨 Check out Beisel Lab’s recent work in Nucleic Acids Res reporting new Anti-CRISPR proteins. They were discovered in a bacterial #pathogen with two extensively self-targeting Type I #CRISPR-Cas systems, and the Acrs block #DNA degradation but not DNA binding.

(2/2) For those and many more intriguing findings, including unexpected homologs, see 👇academic.oup.com/nar/advance-ar…

Job Alerts, thrilled to announce that I will join NUS in Singapore in July 2024! 2 Postdoc and 4 fully-funded PhD positions available. Join me in this beautiful and vibrant place for #CRISPR and beyond research! If interested, email me or DM. Please RT!!!

Our brilliant team member, Chunlei Jiao will start a new adventure with his own lab at NUS in Singapore next year! A huge congratulations to him on this achievement. #CRISPR #PostdocPositions #PhDPositions

Exciting advance addressing a long-standing challenge: efficiently transforming DNA! Congrats to Justin Vento on his new paper introducing IMPRINT. Helmholtz Institute Würzburg (HIRI) ncstatecbe doi.org/10.1016/j.molc…

#CRISPRCas systems have become a plentiful source of technologies for molecular diagnostics. #HIRI’s Beisel Lab has now expanded this extensive toolbox. PUMA enables the detection of RNA with Cas12 nucleases, which naturally target DNA. 🧬🐈🧵 Read more: helmholtz-hiri.de/en/newsroom/ne…

Check out the exciting work of Chunlei Jiao on the PUMA technology for the precise detection of RNA with DNA-cutting Cas12 nucleases

In my publishing my first Spotlight article era ✨️ Beisel Lab

Exciting stuff happening in microbiome science! Check out Charlotte Kamm's Spotlight article on engineering bacteriophages to deliver gene editors.

Excited to share our work published in Nature Biotechnology! We uncover and characterize a unique and highly versatile ancestral form of CRISPR-Cas12a (ReChb)! A big thanks to the whole team. 🧬 nature.com/articles/s4158… #SynBioLab CIC bioGUNE Igor Tascon Beisel Lab FUNDELA

A new research briefing has just been published in Nature Biotechnology, summarizing the latest paper from #HIRI's Beisel Lab in collaboration with Ylenia Jabalera and Raúl Pérez Jiménez from CIC bioGUNE. Check it out! ⤵️

Happy to have been able to contribute to the implementation of this exciting new genome editing tool coming out of the Chase Biesel lab! Beisel Lab Targeted DNA ADP-ribosylation triggers templated repair in bacteria and base mutagenesis in eukaryotes biorxiv.org/content/10.110…