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Fully funded PhD opportunity in my lab cambridge studying the immune responses to pneumonia in the lung & blood. What mechanisms drive lung injury, & how can we treat them. 🧵 below Two options -standard medschl.cam.ac.uk/understanding-… or + industry placement medschl.cam.ac.uk/detection-and-…

Proud to partner with UK Government, Genomics England, UK Biobank, & NHS England to drive genomics-based healthcare in the UK! This initiative supports breakthroughs in patient care, biomedical research, and pandemic preparedness. Read more here: bit.ly/4fsojRa

Hillary Clinton was cold and elitist. Kamala Harris was down-to-earth and laughed too much. Is there always something wrong with women? There must be if a convicted, lying felon can beat them. In Finland we elected a woman president 24 years ago. #USAElection2024

All too often researchers use non-standard methods and so MIC data cannot be reproduced. To reduce that error read this: ‘Antibiotic susceptibility testing using minimum inhibitory concentration (MIC) assays’ ⁦⁦⁦Despoina Mavridou⁩ nature.com/articles/s4425…

Like if you didn't think it was going to be QUITE this bad Retweet if this was all fully expected #RFKJr #Tulsi

Sometimes you think an outbreak is caused by a particular pathogen, and metagenomics reveals it's actually something else. Really interesting investigation (that I played a tiny part in!). Charles Agoti has a great team & pipeline for rapidly solving these mysteries.

🔥The ADAPT-Sepsis RCT🔥 Daily PCT-guided protocol 🔽 total antibiotic duration & had noninferior all-cause mortality compared with standard care. No difference was found in total Abx duration between standard care & daily CRP-guided protocol CRP failure! jamanetwork.com/journals/jama/…

For folks who still believe that CRP test is useful, After ADAPT-SEPSIS RCT, can you now finally declare that the CRP test is useless in Infectious Diseases? Or Do you need more clinical data? Still in doubt: Read our article Brad Spellberg Todd C. Lee clinicalmicrobiologyandinfection.com/article/S1198-…

1/ Delighted to report the results of the Procalcitonin-guided duration of antibiotic treatment in children hospitalised with confirmed or suspected bacterial infection in the UK (BATCH) trial in The Lancet Child & Adolescent Health thelancet.com/journals/lanch…

This absolutely mental.

We’re expanding our reach! Follow us on: Bluesky: @ Inhale-Trial.bsky.social LinkedIn: INHALE trial (linkedin.com/company/inhale…) For all of the latest news from INHALE.

🆕🔥INHALE WP3 RCT 14 ICUs Pts HAP/VAP Provides multi-centre evidence rapid syndromic PCR, delivered at the point-of care in the ICU improved antibiotic stewardship by 21% in absolute terms* Non-inferiority was not demonstrated for cure of pneumonia at 14d link.springer.com/article/10.100…

1/4 Rapid molecular diagnostic tests for pathogens and resistance genes may improve antibiotic prescribing decisions and stewardship. However, clinicians’ desire to protect their patient with an antibiotic often overrides more distal concerns about possible resistance selection,

INHALE compared rapid testing with standard care used to diagnose pneumonia in intensive care. Rapid testing gave faster results than standard care and improvements in antibiotic use. But, the machine did not improve cure of pneumonia, so more research is needed to understand why

What is the impact of seeking pathogens by rapid molecular diagnostic methods on antibiotic stewardship and the clinical outcomes in hospital-acquired and ventilator-associated pneumonia? Visual abstract below and full paper available online at rdcu.be/ehlAu

'INHALE Poem II – A slight diversion’ shares the journey of INHALE, describing its hopes, challenges and implications of the research. This poem was written and performed by Amander Wellings, of the INHALE Patient, Carer and Public Involvement (PPI) group youtu.be/-UUBzbSmEo0?fe…

INHALE WP3 health economic analysis now published in Critical Care. The Pneumonia Panel PCR had lower average ICU costs and was cost effective for antimicrobial stewardship, but not clinical cure. ccforum.biomedcentral.com/articles/10.11…

INHALE WP3 RCT health economic analysis now published in Critical Care. The Pneumonia Panel PCR had lower average ICU costs and was cost effective for antimicrobial stewardship, but not clinical cure. Read in full at: rdcu.be/eAmSD