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Happy to have contributed to this work Journal of Clinical Anesthesia sciencedirect.com/science/articl…

Salar de Uyuni is the world's largest salt flat. Following rain, a thin layer of dead calm water transforms the flat into the world's largest mirror, 129 km across [read more: buff.ly/37Ugxma-] [source, David Houncheringer: buff.ly/370vKSj-]

Study reveals #fentanyl's effects on the brain PNAS Nexus doi.org/gqqswm medicalxpress.com/news/2022-08-r…

Fentanyl’s Effects on the Brain Fentanyl exposure produces specific EEG signatures in the brain. The findings also revealed the drug impairs people's breathing four minutes before noticeable changes in alertness. #neuroscience #science neurosciencenews.com/fentanyls-brai…

Deadliness associated with #DrugMisuse of #fentanyl explained by its causing breathing to stop before sedation kicks in, say researchers from the department of anesthesia of the Massachusetts General Hospital bit.ly/3BfpItq

On this day in 1848, Phineas Gage was working on a railroad when a 7-inch, 13½ pound iron rod was accidentally driven into his head. Amazingly, he survived. His skull, along with the rod, are part of the Warren Anatomical Museum at HMS.

Researchers find a novel electroencephalographic signature highly correlated with fentanyl concentration and respiratory depression. In PNAS Nexus: ow.ly/AGTj50KIbtA

176 years ago today, the 1️⃣ successful public demonstration of the use of ether for surgical anesthesia was performed at MGH. Every year on Oct. 16, we celebrate #EtherDay, the birth of #anesthesiology and the transformation of surgery to a humane and often lifesaving therapy.

Researchers from Department of Anesthesia, Critical Care and Pain Medicine at MassGeneral News and colleagues find that fentanyl produces a unique brain signature, in a PNAS Nexus study. doi.org/10.1093/pnasne…

Excited to share this work finally published PNAS Nexus. We are trying to better understand what the brain tells us under the effects of Fentanyl @MGH_PurdonLab Mass General Anesthesia #Fentanyl #EEG #Opioid academic.oup.com/pnasnexus/arti…

New paper from Fangyun Tian Nature Communications shows that ketamine increases gamma oscillations in frontal and limbic structures, and that propofol can reverse this effect in prefrontal cortical structures. doi.org/10.1038/s41467…

Our study found that reduced opioid administration during surgery may have the unintended outcome of increasing postoperative pain and opioid use. The paper is now out on JAMA Surgery. Read it here: jamanetwork.com/journals/jamas…

PNAS recently published what is hands-down the most detailed study of the relationship between measured personality and intelligence Let's go through it First up: Neuroticism and the General Factor of Personality Intelligence is negatively related to uneven temper and anxiety!

A Narrative Review Illustrating the Clinical Utility of Electroencephalogram-Guided Anesthesia Care in Children 🧠 Well-established clinical management principles in children can be complemented by addition of EEG monitoring. #pedsanes buff.ly/3rLK0bC

Multicenter EHR data from >234k adult non-cardiac surgical patients is used to predict maximum pain after surgery. This #MachineLearning model prospectively outperformed clinicians, & can identify comorbidities that drive postoperative pain. nature.com/articles/s4174…

Thanks to everyone in the The PurdonLab Ryan Nipp, MD, MPH, FASCO Gustavo Balanza Rodrigo Gutiérrez Ran Liu and teams at Mass General Anesthesia Stanford Anesthesiology who helped contribute to this work!

We have officially started collecting data on our Awake EEG and Aging Study which looks at EEG brain activities associated with aging and preclinical Alzheimer's! Here is the study design poster that Amber and Julia presented at the Stanford Anesthesia Department Retreat

Kathleen L Poston Stanford Neurosurgery Stanford Neurology & Neurological Sciences Wu Tsai Neurosciences Institute Stanford Medicine Next up is neuroengineer Patrick Purdon, who discusses whether EEG can serve as a marker of brain resilience. He notes that we still understand little about delirium, but new EEG tools may help track real-time cognitive changes in clinical settings.

A The PurdonLab classic.