Congrats to Xiangwu and all authors on this really interesting work!! 🎉

How to pick a problem. Today in Cell. 1/53 cell.com/cell/fulltext/…

Stunning spring scenery 🌿🌸Rockefeller University and a perfect moment for group photo 😇 From left to right: Qi Jia, Jieru Li, Xiangwu Ju, Stephany Chuquimarca, Htet Ng, Shixin Liu, Yukun Wang, Masuda Begum, John Watters, Gabriella Chua, Jeremy Chang

The 20th annual TPCB Chemical Biology Symposium will be on August 14th and feature keynote speakers Heeseon An An Lab, Carlos Bustamante The Bustamante Lab, Jonathan Long Long Lab and Yamuna Krishnan @KrishnanYamuna! Register for free: bit.ly/TPCB-2024

When Force Met Fluorescence…👯‍♀️ Was grateful for the opportunity to write (and 🧑🏻‍🎨) this review with LiuLab_Rockefeller. Check it out!

🚀 News from the Deindl Lab at Uppsala University! Our latest paper introduces MUSCLE, a new method for high-throughput single-molecule analysis, now featured in Science. 🧬🔬 science.org/doi/10.1126/sc… Science Magazine KAW European Research Council (ERC) SciLifeLab

Our paper on MeCP2 is now published NatureStructMolBiol ! rdcu.be/dRqUn Read the Research Briefing rdcu.be/dRLZf or tweetorial from Gabriella Chua 👇for a summary of the study. And big thanks to the reviewers and editors for their efforts on improving our manuscript.

New findings from LiuLab_Rockefeller provide insight into a master regulator of gene expression, and could open up new avenues for Rett syndrome therapies. #RockefellerScience rockefeller.edu/news/36409-new…

We are pleased to share our latest preprint on bioRxiv! Led by graduate student Lauren Vostal, we use chemical proteomics to profile VCP-DUB interactions in living cells. We identify DUBs that bind the entry, exit, or both sites of VCP's central pore. biorxiv.org/content/10.110…

Congratulations to Christian Baca Christian F. Baca in the Marraffini lab on being recognized by the Max Birnstiel Foundation and Research Institute of Molecular Pathology IMP with an Honourable Mention for the 2024 International Birnstiel Awards! linkedin.com/posts/tpcb_chr…

Really honored to receive this award🤍😊 I was initially drawn to TPCB for my graduate studies because the students were not just scientists; they were also leaders, advocates, & teachers fiercely focused on both science and society. Grateful!

Absolutely thrilled to share our new study, co-led by Puja Majumder and myself, now online in Cell! Here, we characterize a CRISPR-associated adenosine deaminase, Cad1. Incredibly grateful for @MarraffiniLab making it possible. Synopsis below: cell.com/cell/fulltext/…

Using the @LUMICKS C-Trap, the lab of LiuLab_Rockefeller provided unprecedented, real-time insights into the binding behavior of MeCP2, a protein linked to Rett syndrome, across methylated and unmethylated DNA and nucleosomes. lumicks.com/revealing-mecp…

Very happy to share our new review in Molecular Cell covering nucleic acid recognition and effector mechanisms for various prokaryotic immune systems! Was a great experience creating this with @MarraffiniLab! cell.com/molecular-cell…

Scientists in the Alushin_Lab have figured out how cells build a structure that lets them migrate. Unpacking these “finger-like” protein bundles that protrude from cells may lead to novel treatments for metastasis. #RockefellerScience bit.ly/3PKErmA

Some happy news. Pleased to see our paper showing how afadin strengthens cytoskeletal engagement by the cadherin-catenin cell adhesion complex out in Science Advances : bit.ly/3EFpD6h

Vostal et al Kapoor Lab Rockefeller University report two structures of complexes formed by VCP, an unfoldase, & VCPIP1, a deubiquitinase, & suggest that VCPIP1 is poised to cleave #ubiquitin from protein substrates that translocate through VCP’s central pore hubs.la/Q03bV3G00

Our work on single-molecule visualization of mammalian transcription elongation is online NatureStructMolBiol today! Check out the open-access paper rdcu.be/eR257 to see how Pol II acts as a multi-speed machine🚗We are thankful for our collaborators Rockefeller University FuDan University🙏