What causes ACUTE LIVER FAILURE in 2024 ? 🔸Virus, no-viral causes, herbs.... 🔸What are the latest advances to treat this life-threatening condition ? This great review in The Lancet tells you all. t.ly/sEH_X Juan Pablo (JP) Arab, MD  Anand V Kulkarni TheLiverDoc

Highly recommend this amazing program! #livertwitter Liver/Intestinal Community of Practice - AST Women's Health Community of Practice (WHCOP)- AST Liver Fellow Network

We are so excited to welcome 11 new members to join our #LICOP family this month! 🙌 Join us for research, mentorship, networking, and friendship! #LiverTwitter Lindsay Y King Anjana Pillai Howard T. Lee MD FAST Deepika Devuni MD Sarah Khan, MD Jennifer E. Marvin Atoosa Rabiee

In today's #readoftheweek📚, learn why proton pump inhibitor use is not associated with a higher risk of hepatic encephalopathy in patients with #cirrhosis. Read this JHEP Reports article: jhep-reports.eu/article/S2589-… 🙏CLabenz, Simon J. Gairing, Sara Montagnese et al. #LiverTwitter

The full label for #livdelzi is linked below. #LiverTwitter accessdata.fda.gov/drugsatfda_doc…

Highlights of #livdelzi label include DDIs. ✅ avoid with OAT-3 inh (cabotegravir, rifampicin, probenecid) ✅ monitor if on rifampin, CSA ✅ avoid with strong CYP2C19 inh (fluvoxamine, carbamazepine, fluconazole) 🔥 no meaningful interactions with statins #LiverTwitter

#livdelzi for #PBC efficacy highlights ✅ 62% met primary endpoint vs. unprecedented 20% placebo 🔥 25% normalized alkphos vs. 0% placebo 🔥 improvement in objective itch scales likely makes #seladelpar itch beneficial vs. itch neutral #livertwitter nejm.org/doi/full/10.10…

Application deadline for this program extended to 8/23! Don’t miss out #livertwitter Women's Health Community of Practice (WHCOP)- AST AASLD Liver Fellow Network

Alcohol-related liver disease is a case study in health inequality: 🏴󠁧󠁢󠁥󠁮󠁧󠁿 ALD incidence rate increase with increasing deprivation The most deprived neighborhoods experienced the highest absolute increase in incidence from 2001-18 journals.lww.com/ajg/fulltext/2… Peter Jepsen #LiverTwitter

Game changer? What is the potential impact and significance of having the first drug approved for MASH?

Opinion on steps for harmonization of ACLF definitions. Way forward !! #livertwitter

🆕Article in press❕ Identifying the optimal measurement timing and hemodynamic targets of portal pressure gradient after TIPS in patients with cirrhosis and variceal bleeding: a prospective cohort study Read it here👉journal-of-hepatology.eu/article/S0168-… #LiverTwitter

Kudos to Jeffrey V. Lazarus Alina Allen and co for this high yield and incredibly important paper in HEPATOLOGY Journal A must read for you this week #LiverX #livertwitter All that is healthy lifestyle related for those with #MASLD is discussed here: journals.lww.com/hep/abstract/9…

Porto-sinusoidal vascular liver disorder with portal hypertension: Natural History and Long-Term Outcome. - Journal of Hepatology journal-of-hepatology.eu/article/S0168-… Proud of this collaborative effort. Thanks to all VALDIG, ERN centers Hospital Clínic IDIBAPS ERN RARE LIVER CIBERehd

How to combine FIB-4 and Elastography to screen for liver fibrosis ? Which algorithms are proposed by the main liver/GI societies ? I find this summarizing figure very useful. t.ly/V6cvF

Check-out our last article! 🔽 β-blockers lower first decompensation in patients with cirrhosis and enduring portal hypertension after etiological treatment. Madalina Gabriela Taru Horia Stefanescu bogdan procopet The Baveno Cooperation: an EASL Consortium cghjournal.org/article/S1542-…

A how to for multidisciplinary clinics in hepatology doi.org/10.1097/hep.00… in HEPATOLOGY Journal Anjana Pillai

Atoosa Rabiee Jessica Davis

End of the antibiotic prophylaxis era for #cirrhosis

Careful with cancer biomarkers The rarely unravel a differential diagnosis and they can open traps Take Ca19-9 for example Ca19-9 is used to screen for and stage bile duct cancer. But! It can be high from benign obstruction or infection.