(Thrilled to have my first Twitter Thrill) Thrilled to share my first paper published today ⁦Science Magazine⁩. How does a cell monitor metabolic homeostasis across so many subcompartments? We tried to offer a hint by looking at GSH in mitochondria. science.org/doi/10.1126/sc…

Congrats Rebecca Timson for generating a mouse model to study GSH limitation in vivo. Rockefeller University sciencedirect.com/science/articl…

Following up our work describing FLVCR1 as a high affinity choline transporter Kivanc Birsoy Artem Khan, excited to share our recent work in close collaboration with Yeeun Son Hite Lab describing the structure and mechanism of action of FLVCR1! nature.com/articles/s4158…

New work from our lab’s genomics guru Artem Khan with Eric R. Gamazon. Artem generated a new platform for metabolic gene discovery and identified the mitochondrial choline transporter. Rockefeller University Nature Genetics nature.com/articles/s4158…

A novel platform for identifying metabolic gene functions from Kivanc Birsoy has already revealed interactions between proteins and metabolites that are fundamental to cell metabolism. Nature Genetics #RockefellerScience rockefeller.edu/news/36160-new…

Excited to share my first work in Junyue lab describing next generation, imaging free spatial transcriptomics-“IRISeq”. With IRISeq, we are able to perform scalable spatial transcriptomics analysis for various tissue sizes and adjustable resolutions..

Excited to share our perspective on solute carrier transporters - gatekeepers of metabolism sciencedirect.com/science/articl… Kivanc Birsoy Yuyang Liu Gad Tim Kenny Cell Rockefeller University

Happy to share our most recent review on mitochondria-organelle metabolic communication with Shah Lab and Lyssiotis Lab!! We explored aspect of lipid transfer, organelle membrane contacts, ROS, metabolites, and metals! sciencedirect.com/science/articl…

I'm thrilled to share our new #bioRxiv preprint from ⁦Junyue⁩ lab at ⁦Rockefeller University⁩! We present PerturbFate, a high-throughput single-cell CRISPR platform profiling nascent/pre-existing RNA, steady-state RNA & chromatin accessibility. biorxiv.org/content/10.110…

My lab's first paper is out in nature. We show that lipoprotein uptake protects tumors from ferroptosis by delivering the lipid antioxidant α-tocopherol. Surprisingly, tumors use sulfated glycosaminoglycans—not canonical receptors—to capture lipoproteins. nature.com/articles/s4158…

When #AlphaFold2 came out, we wondered: Could it help us understand how enzymes evolve? So we tried it—and it worked! nature.com/articles/s4158…